{"id":19000,"date":"2022-03-03T10:40:28","date_gmt":"2022-03-03T18:40:28","guid":{"rendered":"https:\/\/ameripharmaspe.wpengine.com\/staging\/?p=18685"},"modified":"2026-02-12T15:55:32","modified_gmt":"2026-02-12T22:55:32","slug":"leuprolide-lupron-eligard-fensolvi","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/","title":{"rendered":"Leuprolide (Lupron, Eligard, Fensolvi)"},"content":{"rendered":"\n<p><span style=\"font-weight: 400;\">Leuprolide (pronounced [loo PROE lide]) is also known by the brand names Eligard, Lupron Depot, and Fensolvi.\u00a0 Lupron is an antineoplastic (anti-cancer) drug that belongs to a class called <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/gonadotropin-releasing-hormone-agonist\">gonadotropin-releasing hormone (GnRH) agonists<\/a>. In prostate cancer treatment, Lupron is commonly used as part of <strong>androgen deprivation therapy (ADT)<\/strong>. Lupron is a form of <strong>hormonal therapy<\/strong> that works by lowering the levels of certain hormones in the body, which helps slow or stop the growth of hormone-sensitive cancers.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-87be8f7f97a83fcf386470672b652a44\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Chemo Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#What_Is_Chemotherapy\" >What Is Chemotherapy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Handling_and_Safety_Precautions\" >Handling and Safety Precautions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#How_Is_Lupron_Used\" >How Is Lupron Used?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#What_To_Avoid_While_Taking_Lupron\" >What To Avoid While Taking Lupron<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Pregnancy_and_Lupron\" >Pregnancy and Lupron<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Side_Effects\" >Side Effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Allergic_ReactionHypersensitivity\" >Allergic Reaction\/Hypersensitivity<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Cardiac_Complications\" >Cardiac Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Decreased_Bone_Density\" >Decreased Bone Density<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Endometriosis_Vaginal_Bleeding\" >Endometriosis, Vaginal Bleeding<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Blood_Sugar_Impairment\" >Blood Sugar Impairment<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Pituitary_Apoplexy\" >Pituitary Apoplexy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Psychiatric_Events\" >Psychiatric Events<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Seizures\" >Seizures<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Spinal_Cord_Compression\" >Spinal Cord Compression<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Urinary_Tract_Obstruction\" >Urinary Tract Obstruction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Tumor_Flare\" >Tumor Flare<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#Monitoring\" >Monitoring<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/leuprolide-lupron-eligard-fensolvi\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Chemotherapy\"><\/span>What Is Chemotherapy?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Chemotherapy is a cancer treatment in which certain drugs are used to kill cancerous cells. These drugs are usually cytotoxic chemical substances that are toxic to the cells, restrict their growth, prevent their division, and ultimately kill the cells.&nbsp;<\/span><\/p>\n\n\n\n<p>Lupron differs from traditional chemotherapy because it does not directly kill cancer cells. Instead, it works as a <strong>hormonal (endocrine) therapy<\/strong> by suppressing hormone production, which helps control the growth of hormone-sensitive conditions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Handling_and_Safety_Precautions\"><\/span><strong>Handling and Safety Precautions<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">This medication should be handled with care; therefore, it is important to take appropriate precautions for receiving, handling, storing, administering, and disposing of this medication. It is highly recommended to wear gloves while handling and administering this medication and keep it stored in its original container. Avoid inhalation or contact with skin if damaged or accidentally opened.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Lupron_Used\"><\/span>How Is Lupron Used?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Lupron is approved by the Food and Drug Administration (FDA) for several hormone-related conditions, including hormone-sensitive cancers, gynecologic conditions, and pediatric endocrine disorders.&nbsp;<\/p>\n\n\n\n<p>Lupron may be used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Prostate cancer in men<\/li>\n\n\n\n<li>Breast cancer and endometriosis in women<\/li>\n\n\n\n<li>Certain types of anemia<\/li>\n\n\n\n<li>Central precocious puberty in children<\/li>\n\n\n\n<li>Hormone therapy in transgender females<\/li>\n<\/ul>\n\n\n\n<p><b>Available Formulations<\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">is only available as a solution for intramuscular or subcutaneous injections into the muscle under the skin. It is available in several different dosage strengths, which are available as 1-month, 3-month, 4-month, or 6-month long injections.&nbsp;<\/span><\/p>\n\n\n\n<p><b>Directions for Use<\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Lupron injections can be given every day, once a month, or once every several months, depending on the condition treated. Verify the correct dose and frequency with your provider. The dose should not be more or less than what is prescribed. Most Lupron formulations are administered by a health care provider. Some formulations may be self-administered if specifically instructed by a provider. Wash hands before and after injection.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">General injection administration instructions:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Use a new needle and syringe every time you inject the medicine.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Do not concurrently administer partial doses of different formulations or combine different doses.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Avoid using a combination of syringes to achieve a particular dose.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Choose an injection site that does not have skin discoloration, nodules, lesions, scars, or excess hair.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Avoid areas that may be compressed or rubbed (e.g., belt or waistband area).<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Alternate injection sites periodically.<\/span><\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-cc300ee9cd7508270323e8fee97c49d6\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist About Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Consult a Chemo Specialist<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><span style=\"font-weight: 400;\">Brand-specific injection information:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>Intramuscular Lupron Depot injections<\/b><span style=\"font-weight: 400;\">: Administer within 2 hours of preparation as a single injection into the gluteal area, outer thigh, or upper arm.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Subcutaneous leuprolide acetate injections<\/b><span style=\"font-weight: 400;\">: Inject into areas on the arm, thigh, or abdomen.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Subcutaneous Eligard injections<\/b><span style=\"font-weight: 400;\">: Administer within 30 minutes of preparation to an area with adequate tissue like the upper or mid-abdomen or upper buttocks area.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Subcutaneous Fensolvi injections<\/b><span style=\"font-weight: 400;\">: Fensolvi should be administered by a health care professional as a single subcutaneous injection into the abdomen, upper buttocks, or other location with adequate tissue.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><b>Missed Dose<\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">This medicine must be given on a fixed schedule. If you miss a dose, contact your physician for further instructions immediately.&nbsp;<\/span><\/p>\n\n\n\n<p><b>Storage<\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Store injections in their original containers to protect from light. Store in the refrigerator and do not shake. Allow injection to sit at room temperature for 30 minutes prior to administration. Different formulations have a specified timeframe when they should be administered after reconstitution. It is best to administer injections immediately after reconstitution. Different formulations may have different storage requirements. Read and follow the patient instructions that come with your specific medication.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_To_Avoid_While_Taking_Lupron\"><\/span>What To Avoid While Taking Lupron<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">While taking <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">therapy, you must follow some precautions. Always tell your physician about any medications you are already taking. <\/span><b>Do not take any drug or medicine (even herbals, vitamins, or over-the-counter medications) without prior consent from your physician or pharmacist<\/b><span style=\"font-weight: 400;\">. They may have some significant interactions with leuprolide.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pregnancy_and_Lupron\"><\/span>Pregnancy and Lupron<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Pregnancy status must be checked prior to starting <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">therapy in women of childbearing age. <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">may impair fertility; however, this condition is reversible after discontinuation. Despite the fact that <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">usually inhibits ovulation and stops menstruation, contraception is not guaranteed, and therefore, a nonhormonal contraceptive should be utilized throughout therapy. If pregnant, <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">should be discontinued immediately. It is safest to avoid breastfeeding during <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">therapy.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects\"><\/span>Side Effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">As with any other medication, you may encounter many side effects while taking Lupron. A few things to remember are:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">You may not have all the side effects listed below. Many people may experience little to no side effects.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">The severity of side effects may vary from person to person, so don\u2019t compare your side effects with other people\u2019s experiences.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Most of the side effects will improve when therapy is discontinued.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">These side effects are easily manageable most of the time, either by readjusting the dose of <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">or using additional medications to treat the symptoms. Consult with your physician or pharmacist to explore available options.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Do not hide any symptoms; if you feel any discomfort, do not hesitate to tell your physician or pharmacist about it.<\/span><\/li>\n<\/ul>\n\n\n\n<p><b>Note<\/b><span style=\"font-weight: 400;\">: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-0078802f26b7420b5950df7ee74a25b2\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Chemotherapy Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tChemotherapy\u00a0Financial Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><span style=\"font-weight: 400;\">Some of the more serious side effects of <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">are listed below:<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Allergic_ReactionHypersensitivity\"><\/span><span style=\"font-weight: 400;\">Allergic Reaction\/Hypersensitivity<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">There have been cases reported of patients with allergic reactions to the <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">injection or any of its components. In addition, worsening asthma has been reported in patients with a history of asthma, sinusitis, or allergies. Signs of an allergic reaction can include rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; tightness in the chest or throat; wheezing; difficulty breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. If you are experiencing any of these symptoms, seek emergency medical attention immediately.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cardiac_Complications\"><\/span><span style=\"font-weight: 400;\">Cardiac Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Although uncommon, there is an increased risk for heart attack or stroke in patients with prostate cancer receiving GnRH agonists. <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">can increase the interval between when the heart contracts and relaxes, potentially increasing the risk for cardiac complications.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Decreased_Bone_Density\"><\/span><span style=\"font-weight: 400;\">Decreased Bone Density<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Decreased bone density may be common when using <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">for 6 months or longer. Patients with chronic alcohol or tobacco use, strong family history of osteoporosis, and those taking chronic medications that may decrease bone mineral density are at a higher risk for experiencing decreased bone density, which may eventually lead to bone fractures or falls.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Endometriosis_Vaginal_Bleeding\"><\/span><span style=\"font-weight: 400;\">Endometriosis, Vaginal Bleeding<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">After the first dose of leuprolide, endometriosis symptoms may worsen before being relieved. Female children treated for premature puberty may experience menses or spotting during the first weeks of treatment or after each dose. If bleeding continues after the second month, contact your physician immediately.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Blood_Sugar_Impairment\"><\/span><span style=\"font-weight: 400;\">Blood Sugar Impairment<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Men receiving GnRH agonists are at a higher risk for <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/9815-hyperglycemia-high-blood-sugar\">hyperglycemia<\/a> (high blood glucose), diabetes, or worsening glucose control.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pituitary_Apoplexy\"><\/span><span style=\"font-weight: 400;\">Pituitary Apoplexy<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Although it is rare, a condition called <a href=\"https:\/\/medlineplus.gov\/ency\/article\/001167.htm\">pituitary apoplexy<\/a> may arise with <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">use. This is a condition caused by bleeding inside the pituitary gland of the brain. This may occur anywhere from 1 hour to usually 2 weeks after <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">use. Seek immediate medical attention if you experience a sudden headache, vomiting, vision loss, or visual or mental status changes like confusion, disorientation, or strange behaviors.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Psychiatric_Events\"><\/span><span style=\"font-weight: 400;\">Psychiatric Events<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Psychiatric events are possible with <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">use. Symptoms can include emotional instability, irritability, impatience, depression, anger, and aggression. Patients with a history of psychiatric illness are at a much higher risk for experiencing these symptoms. Contact your physician if you are experiencing any of these symptoms.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Seizures\"><\/span><span style=\"font-weight: 400;\">Seizures<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">It is possible that <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">therapy may increase the risk of seizures in all patients. Patients receiving concomitant medications that may lower the seizure threshold (e.g., certain antidepressants) may be at a higher risk. If seizures occur, contact your physician immediately on how to manage them.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-fcc7749fd4c09381ddcd0d3f629499ad\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tConsult a Chemotherapy Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tGet Chemotherapy Treatment Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Spinal_Cord_Compression\"><\/span><span style=\"font-weight: 400;\">Spinal Cord Compression<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">When used for prostate cancer, <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">may cause spinal cord compression, especially during the first few weeks of therapy. Contact your physician if you are experiencing any of the following symptoms of spinal compression: pain\/stiffness of neck or back, trouble with hand coordination, cramping, numbness, painful sensations, or weakness of the hands, arms, or legs.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Urinary_Tract_Obstruction\"><\/span><span style=\"font-weight: 400;\">Urinary Tract Obstruction<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">When used for prostate cancer, <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">may cause <a href=\"https:\/\/www.britannica.com\/science\/urinary-tract-obstruction\">urinary tract obstruction<\/a>, especially during the first few weeks of therapy. Contact your physician if you are experiencing any of the following symptoms: frequent urination, constant feeling of a full bladder, difficulty urinating, or painful urination.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Tumor_Flare\"><\/span><span style=\"font-weight: 400;\">Tumor Flare<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">When used for prostate cancer, <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">may cause a temporary increase in testosterone (a male hormone), resulting in a condition called a tumor flare. Symptoms of tumor flare include bone pain, blood in urine, or inability or difficulty urinating. This may occur during the first few weeks of therapy in patients with prostate cancer. Consult with your physician on ways to reduce these symptoms.&nbsp;<\/span><\/p>\n\n\n\n<p><b>Other common side effects may include:<\/b><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dizziness or weakness<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Lack of appetite<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Upset stomach or vomiting<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Trouble sleeping<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Injection-site reaction (pain, redness, or swelling)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Back, muscle, or joint pain<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Flu or cold-like symptoms<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Acne<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Mood changes<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Hot flashes\/night sweats<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Vaginal bleeding or discharge<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Monitoring\"><\/span>Monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Due to its many side effects, monitoring is an important part of managing <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">therapy.&nbsp;<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Testosterone and other hormone levels should be periodically monitored at the doctor\u2019s office.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Bone mineral density should also be checked periodically.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Pregnancy status should be checked prior to and during therapy.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Patient should be monitored for the potential development of psychiatric symptoms.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Blood glucose and diabetes status should be regularly monitored.<\/span><\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-87be8f7f97a83fcf386470672b652a44\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Chemo Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Is Lupron a chemo agent?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Lupron is <strong>not a traditional chemotherapy drug<\/strong>. It is classified as a <strong>hormonal therapy<\/strong> and is commonly used in cancer care, particularly for hormone-sensitive prostate cancer. Lupron works by reducing hormone levels in the body rather than directly killing cancer cells.<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">How should Lupron be taken?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">is only available as a solution for intramuscular or subcutaneous injections into the muscle under the skin. <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">injections can be given every day, once a month, or once every several months, depending on the condition treated. Most of the time, it is administered by a health care provider but can be self-administered as well.&nbsp;<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Is Lupron a hormone?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">is not a hormone; rather, it affects the hormones in the body. Estrogen is a hormone found in females that causes cells in the uterus to grow. By reducing estrogen in the body, <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">will stop ovulation and menstrual bleeding, which can help relieve endometriosis. Testosterone, on the other hand, is a hormone found in males and is also suppressed with <\/span><span style=\"font-weight: 400;\">Lupron <\/span><span style=\"font-weight: 400;\">use, reducing symptoms of prostate cancer.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Leuprolide (pronounced [loo PROE lide]) is also known by the brand names Eligard, Lupron Depot, and Fensolvi.  Lupron is an antineoplastic (anti-cancer) drug that belongs to a class called gonadotropin-releasing hormone (GnRH) agonists.<\/p>\n","protected":false},"author":11,"featured_media":19001,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[13],"tags":[11],"class_list":["post-19000","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-dr-dania-jaradat"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Leuprolide (Lupron, Eligard, Fensolvi)<\/title>\n<meta name=\"description\" content=\"Leuprolide (Eligard, Lupron Depot, and Fensolvi) is an anti-cancer drug that belongs to a class called gonadotropin-releasing hormone (GnRH) agonists.\" \/>\n<meta name=\"robots\" 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