{"id":18604,"date":"2022-02-15T10:00:48","date_gmt":"2022-02-15T18:00:48","guid":{"rendered":"https:\/\/ameripharmaspe.wpengine.com\/staging\/?p=18604"},"modified":"2026-01-22T14:15:31","modified_gmt":"2026-01-22T21:15:31","slug":"imatinib-gleevec","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/","title":{"rendered":"Imatinib (Gleevec): Li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau cho b\u1ec7nh b\u1ea1ch c\u1ea7u v\u00e0 c\u00e1c lo\u1ea1i ung th\u01b0 kh\u00e1c"},"content":{"rendered":"\n<p><span style=\"font-weight: 400;\">Imatinib (pronounced [eye MAT eh nib]) is also known by the brand name, Gleevec. Imatinib is an antineoplastic (anti-cancer) drug that belongs to a class called BCR-ABL tyrosine kinase inhibitors. It is a <strong>targeted tyrosine kinase inhibitor (TKI)<\/strong> that works by blocking specific signals cancer cells need to grow and survive.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-47ee01f7dd90e8405e8edda37d69a7b0\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Chemo Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Handling_and_Safety_Precautions\" >Handling and Safety Precautions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#How_Is_Imatinib_Used\" >How Is Imatinib Used?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Available_Formulations\" >Available Formulations<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Directions_for_Use\" >Directions for Use<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Missed_Dose\" >Missed Dose<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Storage\" >Storage<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#What_To_Avoid_While_Taking_Imatinib\" >What To Avoid While Taking Imatinib?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Pregnancy_and_Imatinib\" >Pregnancy and Imatinib<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Imatinib_Side_Effects\" >Imatinib Side Effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Hair_Loss\" >Hair Loss<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Liver_Complications\" >Liver Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Kidney_Complications\" >Kidney Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Bone_Marrow_Suppression_BMS\" >Bone Marrow Suppression (BMS)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Cardiac_Complications\" >Cardiac Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Fluid_Retention\" >Fluid Retention<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#DizzinessDrowsiness\" >Dizziness\/Drowsiness<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#GI_Irritation_or_Bleeding\" >GI Irritation or Bleeding<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Skin_Rash\" >Skin Rash<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Tumor_Lysis_Syndrome_TLS\" >Tumor Lysis Syndrome (TLS)<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#Precautions\" >Precautions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Handling_and_Safety_Precautions\"><\/span><strong>Handling and Safety Precautions<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">This drug is considered to be a hazardous agent, and normally, these pills are covered by a thin coating of material, but if this coating is damaged, removed, melted, or if the pill is broken into pieces, the chemical inside the pill may be irritating to the skin or eyes. Therefore, it is important to take appropriate precautions for receiving, handling, storing, administering, and disposing of this medication. Wash hands after handling tablets and avoid direct contact to the skin or mucous membranes with crushed or broken tablets.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Imatinib_Used\"><\/span>How Is Imatinib Used?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib has been approved by the Food and Drug Administration (FDA) to treat certain types of <a href=\"https:\/\/www.pennmedicine.org\/cancer\/types-of-cancer\/leukemia\/chronic-myeloid-leukemia\/what-is-cml\">chronic myeloid leukemia<\/a> (CML), acute lymphoblastic leukemia (ALL), gastrointestinal stromal tumors (GIST), and certain other rare cancers and blood disorders.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Available_Formulations\"><\/span>Available Formulations<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib is available in the form of oral tablets only. The tablets are available in two different strengths: 100 mg and 400 mg. <\/span><span style=\"font-weight: 400;\">Typically, the dose should not exceed 600 mg daily and will depend on the type of disease being treated. The dose will also depend on whether you have other conditions, such as kidney or liver damage (the dose will be adjusted according to kidney or liver function).<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Directions_for_Use\"><\/span>Directions for Use<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib is typically dosed once a day, ranging between 100 mg to 600 mg per dose, depending on cancer type and severity. The dose and schedule are determined by the provider and should be followed exactly as prescribed.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Administer dose with a meal and a large glass of water. While taking the tablet, swallow it whole; do not break, crush, chew, or allow it to be dissolved in your mouth. Avoid skin contact with crushed tablets; if contact occurs, wash thoroughly.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Tablets may be dispersed in water or apple juice using:&nbsp;<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">50 ml for a 100 mg tablet&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">200 ml for a 400 mg tablet<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Stir until the tablet dissolves and administer immediately. To ensure the full dose is administered, add more water to rinse the glass and administer. Do NOT disperse in grapefruit juice.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib tablets can be made into an oral suspension with Ora-Sweet. Shake the suspension well before use and be aware of the date of use.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Missed_Dose\"><\/span>Missed Dose<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">If you miss a dose of this medicine, skip the missed dose and take your next dose when you normally would. Do not take extra medicine to make up for a missed dose.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Storage\"><\/span>Storage<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Store tablets in a cool, dry place at room temperature and ensure the bottle is tightly closed. The oral suspension, once made, is stable for up to 14 days refrigerated or at room temperature.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-f40c5d52b1b652fb6836454b9a3f1423\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist About Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Consult a Chemo Specialist<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_To_Avoid_While_Taking_Imatinib\"><\/span>What To Avoid While Taking Imatinib?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">While taking imatinib therapy, you must follow some precautions. Always tell your physician about any medications you are already taking. <\/span><b>Do not take any drug or medicine (even herbals, vitamins, or over-the-counter medications) without prior consent from your physician or pharmacist<\/b><span style=\"font-weight: 400;\">. They may have some significant interactions with imatinib. <\/span><span style=\"font-weight: 400;\">Avoid grapefruit, grapefruit juice, and any foods or supplements containing grapefruit or grapefruit juice throughout therapy as they may interact with the medication as well.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pregnancy_and_Imatinib\"><\/span>Pregnancy and Imatinib<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Pregnancy status must be checked prior to starting imatinib therapy in women of childbearing age, and effective contraception must be used during treatment and for 2 weeks after the last dose. Imatinib may cause fetal harm and is therefore not recommended for women who are breastfeeding during therapy. Breastfeeding should also be avoided for at least 1 month after the last dose.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Imatinib_Side_Effects\"><\/span>Imatinib Side Effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">As with any other medication, you may encounter side effects while taking imatinib. A few things to remember are:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">You may not have all the side effects listed below. Many people may experience little to no side effects.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">The severity of side effects may vary from person to person, so don\u2019t compare your side effects with other people\u2019s experiences.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Most of the side effects will improve when therapy is discontinued.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">These side effects are easily manageable most of the time, either by readjusting the dose of <\/span><span style=\"font-weight: 400;\">imatinib <\/span><span style=\"font-weight: 400;\">or using additional medications to treat the symptoms. Consult with your physician or pharmacist to explore available options.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Do not hide any symptoms; if you feel any discomfort, do not hesitate to tell your physician or pharmacist about it.<\/span><\/li>\n<\/ul>\n\n\n\n<p><b>Note<\/b><span style=\"font-weight: 400;\">: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Some of the more serious side effects of imatinib are listed below:<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hair_Loss\"><\/span><span style=\"font-weight: 400;\">Hair Loss<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Hair thinning or mild hair loss may occur with imatinib, but complete hair loss is uncommon. When hair changes do occur, they are usually mild and reversible. Hair typically regrows after treatment is adjusted or discontinued.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Liver_Complications\"><\/span><span style=\"font-weight: 400;\">Liver Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">In certain cases, imatinib can affect the liver and cause liver damage. The condition of the liver is monitored through blood tests that are able to detect liver function. Contact your physician immediately if you experience liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin or eyes. These may be indications of liver complications.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Kidney_Complications\"><\/span><span style=\"font-weight: 400;\">Kidney Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib may cause kidney complications, leading to kidney dysfunction. Kidney status can be monitored by taking a urine test at the doctor\u2019s office. Contact your physician if you are experiencing any inability to pass urine, changes in how much urine is passed, blood in the urine, or a sudden weight gain.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-6be693c50199f19719fe15d401369db0\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Chemotherapy Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tChemotherapy\u00a0Financial Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Bone_Marrow_Suppression_BMS\"><\/span><span style=\"font-weight: 400;\">Bone Marrow Suppression (BMS)<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">It is essential to keep up with regular blood tests, especially the complete blood count test (CBC). The CBC blood test is capable of detecting BMS, including <a href=\"https:\/\/www.mdanderson.org\/patients-family\/diagnosis-treatment\/emotional-physical-effects\/neutropenia.html\">neutropenia<\/a> (low neutrophils, a type of white blood cell), <a href=\"https:\/\/www.merckmanuals.com\/home\/blood-disorders\/platelet-disorders\/overview-of-thrombocytopenia\">thrombocytopenia<\/a> (low platelet count), and anemia (low red blood cells), all of which are potential side effects from the use of imatinib. BMS is typically prevalent within the first few months of starting therapy. Blood counts are monitored regularly, especially during the first few months of therapy. The monitoring schedule is determined by the treating provider.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cardiac_Complications\"><\/span><span style=\"font-weight: 400;\">Cardiac Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">There may be cardiac complications with the use of imatinib, such as <a href=\"https:\/\/www.netmeds.com\/health-library\/post\/left-ventricular-dysfunction-causes-symptoms-and-treatment\">left ventricular dysfunction<\/a> (LVD) or heart failure. Complication risk is increased in patients with existing comorbidities, other cardiac risk factors, or a history of renal failure.\u00a0 Due to the severity of these side effects, regular monitoring of heart and kidney function may be warranted, such as with an echocardiogram or renal testing.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Fluid_Retention\"><\/span><span style=\"font-weight: 400;\">Fluid Retention<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib can commonly cause fluid retention (also known as edema) and weight gain. Edema may lead to significant complications, including liver or heart complications and edema in the lungs. Rapid weight gain or swelling of the abdomen, legs, feet, or arms can all be signs of fluid retention. Contact your physician if you experience any of these symptoms.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"DizzinessDrowsiness\"><\/span><span style=\"font-weight: 400;\">Dizziness\/Drowsiness<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib can cause dizziness, drowsiness, fatigue, feelings of tiredness, and blurred vision. Driving or operating heavy machinery while taking imatinib is not advised.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"GI_Irritation_or_Bleeding\"><\/span><span style=\"font-weight: 400;\">GI Irritation or Bleeding<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">GI irritation like upset stomach or nausea may occur with imatinib use. Taking imatinib with food and water may help reduce GI irritation effects. Although rare, severe bleeding, including GI hemorrhage and tumor hemorrhage, is possible with Imatinib use. Contact your physician immediately if you experience vomiting or coughing blood; vomit that looks like coffee grounds; blood in urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a reason or that get bigger; or any severe or persistent bleeding.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Skin_Rash\"><\/span><span style=\"font-weight: 400;\">Skin Rash<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">On rare occasions, Imatinib may cause a serious skin reaction called <\/span><span style=\"font-weight: 400;\">Stevens-Johnson syndrome (SJS) or <\/span><a href=\"https:\/\/www.drugs.com\/cg\/toxic-epidermal-necrolysis.html\"><span style=\"font-weight: 400;\">toxic epidermal necrolysis<\/span><\/a><span style=\"font-weight: 400;\"> (TEN). These rashes may appear as red, swollen, hives; itching, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes. Notify your physician or pharmacist immediately of any signs of a rash or allergic reaction, including wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Discontinuation of imatinib should be warranted if SJS or TEN is suspected.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Tumor_Lysis_Syndrome_TLS\"><\/span><span style=\"font-weight: 400;\">Tumor Lysis Syndrome (TLS)<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7426989\/\">TLS<\/a> is caused by the rapid breakdown of cancer cells (bursting of the cells). TLS can cause you to have kidney failure with the need for dialysis treatment or an abnormal heart rhythm. Certain types of conditions are at higher risk for TLS. Consult with your physician to learn more. Tell your healthcare provider right away if you have any of the following signs or symptoms of TLS: trouble passing urine, abnormal heartbeat, passing out, muscle weakness or cramping, constant fatigue, diarrhea, or inability to eat.<\/span><\/p>\n\n\n\n<p><b>Other common side effects<\/b> <b>may include:<\/b><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Gas<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dry skin<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Changes in taste<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nose or throat irritation<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Back or joint pain<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Muscle spasm<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Weight gain&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Anxiety<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Night sweats<\/span><\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-6e638801a91826ddef986c851f2b37cf\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tConsult a Chemotherapy Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tGet Chemotherapy Treatment Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precautions\"><\/span>Precautions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Extra monitoring may be necessary for certain patients.<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>Kidney Failure: <\/b><span style=\"font-weight: 400;\">Patients are at a higher risk for kidney failure if they have other medical conditions such as:<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Preexisting kidney complications<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Heart failure&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><b>Growth Impediment:<\/b><span style=\"font-weight: 400;\"> Prepubescent children receiving imatinib are at high risk for growth delays in terms of decreased weight (decreased BMI) and delay in height growth. Growth should be monitored closely. Typically, once puberty is reached, normal growth patterns should be restored.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Fluid Retention (Edema):<\/b><span style=\"font-weight: 400;\"> There is a higher risk for fluid retention if the patient is:&nbsp;<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Over 65 years old<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Receiving high imatinib doses<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Is imatinib a chemo agent?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib is <strong>not traditional <\/strong><a href=\"https:\/\/ameripharmaspecialty.com\/oral-chemotherapy-cancer-drugs\/\"><strong>chemotherapy<\/strong><\/a>. It is a targeted tyrosine kinase inhibitor that blocks specific cancer growth signals.<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">How should imatinib be taken?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Administer dose with a meal and a large glass of water. While taking the tablet, swallow it whole; do not break, crush, chew, or allow it to be dissolved in your mouth. Tablets can be mixed in water or apple juice. Do NOT mix with grapefruit juice. Imatinib can also be made into an oral suspension with Ora-Sweet. Shake the suspension well before use and consume within 14 days.&nbsp;<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Can you lose your hair with imatinib?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Hair thinning or mild hair loss may occur with imatinib, but complete hair loss is uncommon.<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Can you touch imatinib?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Imatinib tablets should be handled carefully. Avoid crushing or breaking tablets, and wash your hands after handling. If assistance is needed, wearing gloves may help minimize direct contact.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imatinib (pronounced [eye MAT eh nib]) is also known by the brand name, Gleevec. Imatinib is an antineoplastic (anti-cancer) drug that belongs to a class called BCR-ABL tyrosine kinase inhibitors. It is a targeted tyrosine kinase inhibitor (TKI) that works by blocking specific signals cancer cells need to grow and survive.<\/p>\n","protected":false},"author":11,"featured_media":18606,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[13],"tags":[11],"class_list":["post-18604","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-dr-dania-jaradat"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Imatinib (Gleevec): A Targeted Therapy for Leukemia and Other Cancers - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Imatinib (Gleevec) is an antineoplastic (anti-cancer) drug that belongs to a class called BCR-ABL tyrosine kinase inhibitors.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/imatinib-gleevec\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Imatinib (Gleevec): A Targeted Therapy for Leukemia and Other Cancers - 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