{"id":17412,"date":"2021-11-17T07:19:51","date_gmt":"2021-11-17T15:19:51","guid":{"rendered":"https:\/\/ameripharmaspe.wpengine.com\/?p=17412"},"modified":"2025-12-30T17:19:41","modified_gmt":"2025-12-31T00:19:41","slug":"acalabrutinib-calquence","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/","title":{"rendered":"Acalabrutinib (Calquence)"},"content":{"rendered":"\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#What_Is_Acalabrutinib\" >What Is Acalabrutinib?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#What_Is_Targeted_Therapy\" >What Is Targeted Therapy?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#How_Is_Calquence_Used\" >How Is Calquence Used?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Available_Formulations\" >Available Formulations<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Directions_for_Use\" >Directions for Use<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Missed_Dose\" >Missed Dose<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Storage\" >Storage<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#What_To_Avoid_While_Taking_Calquence\" >What To Avoid While Taking Calquence?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Pregnancy_and_Calquence\" >Pregnancy and Calquence<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Side_Effects\" >Side Effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Nausea_and_Vomiting\" >Nausea and Vomiting<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Diarrhea_or_Abdominal_Pain\" >Diarrhea or Abdominal Pain<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Bleeding_Complications\" >Bleeding Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Infection_Risk\" >Infection Risk<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Blood_Count_Changes\" >Blood Count Changes<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Heart_Rhythm_Complications\" >Heart Rhythm Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Secondary_Malignancies\" >Secondary Malignancies<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Other_common_side_effects_may_include\" >Other common side effects may include:<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#Precautions\" >Precautions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Acalabrutinib\"><\/span>What Is Acalabrutinib?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Acalabrutinib (pronounced [a KAL a broo ti nib]) is also known by the brand name, Calquence. It is a targeted anticancer therapy (an antineoplastic drug) that belongs to a class called <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/btk-inhibitor\">Bruton\u2019s tyrosine kinase (BTK) inhibitors<\/a>. BTK inhibitors work by blocking Bruton\u2019s tyrosine kinase (BTK), a protein involved in signaling pathways that help certain B-cells survive and grow. Follow your clinic\/pharmacy\u2019s handling instructions for antineoplastic medications. Wash hands after handling and keep tablets out of reach of children and pets.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Targeted_Therapy\"><\/span><strong>What Is Targeted Therapy?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Targeted therapy is a cancer treatment that blocks specific proteins or signals that help cancer cells grow and survive. Unlike traditional chemotherapy, many targeted therapies are not broadly cytotoxic to rapidly dividing cells, though they can still cause significant side effects.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Calquence_Used\"><\/span>How Is Calquence Used?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Calquence is FDA-approved to treat certain B-cell blood cancers, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mantle cell lymphoma (MCL) in specific settings. Calquence may be used alone or in combination with other anticancer medicines (for example, with <a href=\"https:\/\/reference.medscape.com\/drug\/gazyva-obinutuzumab-999895\">obinutuzumab<\/a> for CLL\/SLL, or with bendamustine and <a href=\"https:\/\/ameripharmaspecialty.com\/cancer\/rituximab-rituxan\/\">rituximab<\/a> for certain patients with previously untreated MCL).<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Available_Formulations\"><\/span>Available Formulations<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Calquence is available as oral tablets. The tablets are available in a 100 mg strength. The tablets are orange, oval, film-coated, and debossed with \u201cACA 100\u201d on one side. Calquence is dosed twice a day, and the dose is dependent on the cancer type or severity and other factors. Verify the correct dose and frequency with your provider.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Directions_for_Use\"><\/span>Directions for Use<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Calquence may be taken with or without food, but it should be taken with water. When taking the tablet, swallow it whole with water; do not break, crush, or chew it. If taken in combination with obinutuzumab (Gazyva), which is given intravenously, it is best to take Calquence at least one hour prior to the infusion.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Missed_Dose\"><\/span>Missed Dose<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">If you accidentally miss a dose, and it has been more than 3 hours, skip the missed dose and continue with the next scheduled dose. Do not take extra doses to make up for a missed dose. <\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Storage\"><\/span>Storage<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Store capsules in a cool, dry place at room temperature and ensure the bottle is tightly closed.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_To_Avoid_While_Taking_Calquence\"><\/span>What To Avoid While Taking Calquence?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>While on Calquence therapy, you must follow some precautions. Always tell your physician about any medications you are already taking. <strong>Do not take any drug or medicine (even herbals or over-the-counter medications) without prior consent from your physician or pharmacist, as they may have significant interactions with Calquence.&nbsp;<\/strong><\/p>\n\n\n\n<p>Do not receive any vaccinations (especially live vaccines) without first discussing it with your oncology team. They can advise you on timing and which vaccines are appropriate during treatment. Minimize sun exposure and use sunblock while outside. Tell your care team if you take acid-reducing medicines (antacids, H2 blockers like famotidine, or <a href=\"https:\/\/www.health.harvard.edu\/newsletter_article\/proton-pump-inhibitors\">proton pump inhibitors<\/a>\/PPIs like omeprazole). Your pharmacist or oncology team will advise you on the best way to take Calquence with these medicines, if needed.<\/p>\n\n\n\n<p>Avoid grapefruit, grapefruit juice, and any foods or supplements containing grapefruit or grapefruit juice throughout therapy as they may also interact with the medication. Ask your care team about alcohol use during treatment, especially if you have bleeding risk, liver problems, or are taking other medicines that increase bleeding. It may be necessary to discontinue Calquence 3 to 7 days before any scheduled surgeries.<span style=\"font-weight: 400;\"> <\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pregnancy_and_Calquence\"><\/span>Pregnancy and Calquence<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Pregnancy status must be checked prior to starting treatment in women of childbearing age. Effective contraception must be used during treatment and for 1 week after the last dose. Calquence may cause fetal harm and is therefore not recommended for women who are breastfeeding during therapy. Breastfeeding should also be avoided for at least 2 weeks after the last dose.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects\"><\/span>Side Effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">As with any other medication, you may encounter many side effects while taking Calquence. A few things to keep in mind are:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">You may not have all the side effects listed below. Many people may experience little to no side effects.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">The severity of side effects may vary from person to person, so don&#8217;t compare your side effects with other people\u2019s experiences.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Most of the side effects will improve when therapy is discontinued.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">These side effects are easily manageable most of the time either by readjusting the dose of Calquence or using additional medications to treat the symptoms. Consult with your physician or pharmacist to explore available options.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Do not hide any symptoms; when you feel any discomfort, do not hesitate to tell your physician or pharmacist about it.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><b>Note<\/b><span style=\"font-weight: 400;\">: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Some of the most common side effects of Calquence are:&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Nausea_and_Vomiting\"><\/span><span style=\"font-weight: 400;\">Nausea and Vomiting<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">You may experience nausea and vomiting after starting treatment. These symptoms usually disappear after a few hours or days after starting therapy. If nausea or vomiting is severe, contact your physician to see if they can add an <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/320384\">antiemetic medication<\/a> to the regimen. Eating habits should consist of small amounts of food 4 to 6 times a day. Try to avoid eating too much at once. Maintain proper body hydration and drink fluids throughout the day. Nausea and vomiting may result in abdominal pain and can also cause a decrease in appetite, leading to weight loss.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diarrhea_or_Abdominal_Pain\"><\/span><span style=\"font-weight: 400;\">Diarrhea or Abdominal Pain<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">If you have watery stools more than four times a day or frequent loose, watery stools, you may have diarrhea. This is one of the most common side effects of Calquence. Abdominal pain may be associated with diarrhea. Stay hydrated and take plenty of fluids to maintain the water balance of your body. If you have diarrhea, choose bland, low-fiber foods and avoid foods that commonly worsen diarrhea (such as greasy\/fried foods, spicy foods, high-fiber foods, and dairy if it bothers you). As symptoms improve, gradually return to your usual diet based on your tolerance. Examples of foods that are often easier to tolerate include bananas, rice, applesauce, toast, plain pasta, and baked\/boiled lean proteins. In rare cases, diarrhea may get severe. If that happens, consult your doctor immediately. Patients 60 years or older may experience a greater incidence of these side effects.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Bleeding_Complications\"><\/span><span style=\"font-weight: 400;\">Bleeding Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Bleeding problems may occur including bruising; black, tarry, or bloody stools; bleeding gums; blood in the urine; coughing up blood; cuts that take a long time to stop bleeding; feeling dizzy, tired, or weak; nosebleeds; pain or swelling; increased menstrual flow; throwing up blood; vomit that looks like coffee grounds; or a very bad headache. These side effects can potentially lead to serious hemorrhagic events; therefore, inform your physician if any of these bleeding complications appear. It may be necessary to discontinue Calquence 3 to 7 days before any scheduled surgeries.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Infection_Risk\"><\/span><span style=\"font-weight: 400;\">Infection Risk<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">There may be a high chance of acquiring an infection while on Calquence therapy. Infections may include fungal, bacterial (like pneumonia), or viral infections (like hepatitis B). If previously infected with hepatitis B, using Calquence may lead to the reactivation of the viral infection. In order to minimize the risk of infection, it is important to avoid crowds, unhygienic street foods, certain vaccines, etc. Early symptoms of infection may include cough, chills, fever, flu, or trouble breathing. If you acquire any infection, immediately seek advice from your physician.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Blood_Count_Changes\"><\/span><span style=\"font-weight: 400;\">Blood Count Changes<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Your care team may monitor your blood counts with periodic labs (such as a complete blood count\/CBC). Calquence can sometimes cause decreases in blood cells, including leukopenia (low white blood cells), neutropenia (low neutrophils), thrombocytopenia (low platelets), and anemia (low red blood cells).<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Heart_Rhythm_Complications\"><\/span><span style=\"font-weight: 400;\">Heart Rhythm Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">There is a risk that Calquence may cause heart rhythm complications like atrial fibrillation or atrial flutter. Symptoms may present as shortness of breath, irregular heartbeat, chest discomfort, or dizziness. Risk is higher in patients with a history of high blood pressure or arrhythmias.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Secondary_Malignancies\"><\/span><span style=\"font-weight: 400;\">Secondary Malignancies<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">It is possible that Calquence can give rise to a secondary type of cancer during treatment. The most common cancer is skin cancer, which is why it is essential to avoid the sun during therapy and use sunscreen while outdoors. If any new lumps or moles appear on the skin, consult your physician immediately.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Other_common_side_effects_may_include\"><\/span>Other common side effects may include:<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Muscle tenderness or pain<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Skin rash&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Bruising<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Neck, joint, or bone pain<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precautions\"><\/span>Precautions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Unless approved by your physician, Calquence is generally not recommended in:&nbsp;<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Patients who have an allergy to Calquence. Allergic reactions can cause a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around your mouth or eyes, fast heart rate, trouble breathing, and sweating. If you have any of these symptoms, stop using Calquence and call your doctor or get emergency help right away.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Patients with a risk of high blood pressure or a history of <a href=\"https:\/\/www.nhlbi.nih.gov\/health-topics\/arrhythmia\">arrhythmias<\/a>. Blood pressure should be monitored regularly.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Patients undergoing elective surgery. Calquence may need to be discontinued 3 to 7 days before and after scheduled surgeries.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Is Calquence a chemo agent?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Calquence (acalabrutinib) is generally considered a targeted therapy (a BTK inhibitor), not traditional chemotherapy. It works by blocking BTK signaling that can help certain cancerous B-cells survive and grow.<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">What is the best time to take Calquence?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Calquence may be taken with or without food, but should be taken with water. When taking the tablet, swallow it whole with water; do not break, crush, or chew it. If taken in combination with obinutuzumab (Gazyva), which is given intravenously, it is best to take Calquence at least 1 hour prior to the infusion.<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Is Acalanritinib available as a generic?<\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Currently, acalabrutinib is not available as a generic. It is only available as the brand, Calquence.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Acalabrutinib (pronounced [a KAL a broo ti nib]) is also known by the brand name, Calquence. It is a targeted anticancer therapy (an antineoplastic drug) that belongs to a class called Bruton\u2019s tyrosine kinase (BTK) inhibitors.<\/p>\n","protected":false},"author":11,"featured_media":17729,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[13],"tags":[11],"class_list":["post-17412","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-dr-dania-jaradat"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Acalabrutinib (Calquence) - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Acalabrutinib (Calquence) is a type of chemotherapy and an antineoplastic (anticancer) drug that belongs to a class called tyrosine kinase inhibitors (TKI).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/acalabrutinib-calquence\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Acalabrutinib (Calquence) - 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C\u00f4 t\u1ed1t nghi\u1ec7p \u0110\u1ea1i h\u1ecdc Marshall B. Ketchum. \u0110i\u1ec1u b\u1ed5 \u00edch nh\u1ea5t trong c\u00f4ng vi\u1ec7c c\u1ee7a c\u00f4 l\u00e0 duy tr\u00ec m\u1ed1i quan h\u1ec7 c\u1edfi m\u1edf gi\u1eefa d\u01b0\u1ee3c s\u0129 v\u00e0 b\u1ec7nh nh\u00e2n, \u0111\u1ed3ng th\u1eddi h\u01b0\u1edbng d\u1eabn b\u1ec7nh nh\u00e2n v\u1ec1 c\u00e1ch qu\u1ea3n l\u00fd thu\u1ed1c. Trong th\u1eddi gian r\u1ea3nh r\u1ed7i, c\u00f4 th\u00edch \u0111i du l\u1ecbch \u0111\u1ebfn nhi\u1ec1u qu\u1ed1c gia kh\u00e1c nhau, d\u00e0nh th\u1eddi gian cho ch\u1ed3ng v\u00e0 con trai, v\u00e0 \u0111\u1ecdc s\u00e1ch. Xem Ti\u1ec3u s\u1eed T\u00e1c gi\u1ea3","url":"https:\/\/ameripharmaspecialty.com\/vi\/author\/dania-jaradat\/"}]}},"uagb_featured_image_src":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence.jpg",1280,679,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-300x159.jpg",300,159,true],"medium_large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-768x407.jpg",768,407,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-1024x543.jpg",1024,543,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence.jpg",1280,679,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence.jpg",1280,679,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence.jpg",18,10,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence.jpg",600,318,false],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-86x46.jpg",86,46,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-167x89.jpg",167,89,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-280x149.jpg",280,149,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-370x196.jpg",370,196,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence-960x509.jpg",960,509,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2021\/11\/acalabrutinib-calquence.jpg",1280,679,false]},"uagb_author_info":{"display_name":"Dr. Dania Jaradat, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/dania-jaradat\/"},"uagb_comment_info":1,"uagb_excerpt":"Acalabrutinib (pronounced [a KAL a broo ti nib]) is also known by the brand name, Calquence. 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It is a targeted anticancer therapy (an antineoplastic drug) that belongs to a class called Bruton\u2019s tyrosine kinase (BTK) inhibitors.","_links":{"self":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/17412","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/comments?post=17412"}],"version-history":[{"count":0,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/17412\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media\/17729"}],"wp:attachment":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media?parent=17412"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/categories?post=17412"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/tags?post=17412"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}