Hướng dẫn sử dụng

Food may decrease the absorption of temozolomide. Therefore, it is preferable to take this medication on an empty stomach. If experiencing nausea or vomiting, it may be best to administer on an empty stomach or at bedtime. It should be taken at the same time each day. If taking temozolomide with concurrent radiation therapy, the medication may need to be taken in a fasted state one hour prior to radiotherapy, but verify the correct dose and frequency with your provider. The dose should not be more or less than what is prescribed.

While taking the capsule, swallow it whole; do not open, break, crush, chew, or allow it to be dissolved in your mouth. Swallow the capsules with a full glass of water. If vomiting occurs, do not readminister the dose again and wait until the next scheduled dose. If the capsules are opened or damaged, avoid inhalation or contact with the skin or mucous membranes.

For the intravenous solution, the goal is to infuse over 90 minutes. Flush the line before and after administration. Temozolomide may be administered through the same IV line as normal saline. Do not administer other solutions or medications through the same IV line.