Paano Gumagana ang Tulong

Pag-streamline ng karanasan sa parmasya ng espesyalidad ng aming pasyente na may walang kaparis na kaginhawaan ng buong serbisyo

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    1. Suriin ang Iyong Pag-verify ng Saklaw/Mga Benepisyo

    Nahanap ng aming team ng mga ekspertong biller ang pinakamahusay na mga paraan ng coverage na nagpapaliit sa mga gastos mula sa bulsa.

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    2. Ilipat ang Reseta sa AmeriPharma®

    Pinoproseso namin ang iyong reseta sa pamamagitan ng pakikipagtulungan sa iyong nakaraang parmasya o tagapagreseta, na ginagawang mabilis at madali ang paglipat.

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    3. Paunang Awtorisasyon

    Ang aming pangkat ng mga espesyalista ay nakakakuha ng pag-apruba mula sa iyong mga kompanya ng seguro sa loob ng 24 hanggang 72 oras.

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    4. Tulong sa Copay at Tulong Pinansyal

    Tinitiyak namin ang tulong pinansyal at binabawasan ang mga copay, mula sa bulsa na gastos, at mataas na deductible. Sa ngayon, ang AmeriPharma® Specialty Care ay nakakuha ng $55 milyon na tulong pinansyal para sa aming mga pasyente.

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    5. Koordinasyon ng Pangangalaga sa Pag-aalaga Kung Kailangan

    Inuuna ng AmeriPharma® ang iyong iskedyul at kapaligiran sa bahay kapag nag-iiskedyul at nag-coordinate ng isa sa aming mga dalubhasang nars para sa iyong mga in-home infusions.

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    6. Koordinasyon sa Paghahatid

    Ang mga gamot ay palaging inihahatid sa mahigpit na pagsunod sa mga partikular na kinakailangan para sa pagpapadala. Ang mga susunod na araw at magdamag na cold-chain na mga paghahatid ay pinag-ugnay sa iyong iskedyul.

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What Is Reblozyl?

Reblozyl, also known by its generic name “luspatercept,” is a prescription drug used to treat symptoms of anemia (low red blood cell counts) in adult patients suffering from blood disorders such as myelodysplastic syndrome (MDS) and beta-thalassemia.

Reblozyl belongs to the drug class of “erythroid maturation agents” (EMA) that works to improve the erythropoiesis process (a process involved in the production of mature red blood cells). In other words, it works by creating more mature, working red blood cells (RBCs) and allows immature cells to mature and work the correct way. This improves the quality of RBCs and increases the amount of hemoglobin (Hgb) in the body, resulting in the improvement of anemia because there are more mature RBCs in the bloodstream. Reblozyl is the only drug of this class that is FDA-approved for treating anemia in adult patients who require regular red blood cell (RBC) transfusions or whose anemia does not respond well to other erythroid maturation agents.

Reblozyl can only be obtained through a doctor’s prescription and is available in single-dose vials for injection purposes in two different strengths: 25 mg and 75 mg.

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What Is Reblozyl Used To Treat?

Reblozyl has been approved as a first-class therapy to treat anemia associated with the following blood disorders in adults:

  • Beta thalassemia – a rare type of inherited blood disorder in which patients either have missing or defective genes that make beta globin protein. This protein is a component of hemoglobin protein present in RBCs which carries oxygen around the body. When you have thalassemia, your body is making less hemoglobin than normal, and it can result in mild or severe anemia. When hemoglobin levels are low, it can cause muscle weakness, fatigue, and many more serious complications. Reblozyl is indicated in adult patients with beta thalassemia who require regular RBC transfusions.
  • Myelodysplastic syndrome (MDS) – a group of cancers in which immature blood-forming cells in the bone marrow do not develop (mature) or become healthy functional cells. The most common cells affected by MDS are red blood cells. When immature cells do not work the way that they should, this leaves less room for healthy white blood cells (WBCs), RBCs, and platelets to form in the bone marrow. Anemia, infection, or easy bleeding can occur as a result of fewer healthy blood cells.

Copay at Tulong Pinansyal

Ang AmeriPharma™ Specialty Pharmacy ay nagpapagaan ng mga pasanin sa pananalapi para sa mga pasyente at kanilang mga pamilya

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    Hinahanap ng advanced na software ang mga pinagmumulan ng pagpopondo upang itugma ka sa mga programang pundasyon ng nangungunang dolyar

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    Isa sa aming mga espesyalista sa tulong sa copay ay tutulong sa proseso ng aplikasyon

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    Ang mga awtomatikong update ay ipapadala sa iyo at sa iyong doktor sa katayuan ng pagpopondo

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Reblozyl Dosing Information

The dose of Reblozyl is adjusted according to the patient’s body weight, hemoglobin, and transfusion records. The recommended initial dose of Reblozyl is 1 mg/kg once every 3 weeks.

Dose Modification for B-thalassemia Patients 

The future doses are modified under the following conditions:

  • If the patient shows insufficient response to the initial dose (1 mg/kg once every 3 weeks) and does not achieve a reduction in RBC transfusions after two treatments ( at least 2 consecutive doses/6 weeks), the dose can be increased to 1.25 mg/kg once every 3 weeks (maximum dose).
  • Discontinue the treatment if patients show insufficient response to the modified dose (1.25 mg/kg) and do not achieve a reduction in RBC transfusions after three treatments (3 doses/9 weeks).

Dose Modification for MDS Patients 

The future doses are modified under the following conditions:

  • If the patient shows insufficient response to the initial dose (1 mg/kg) and does not achieve a reduction in RBC transfusions after two treatments (2 doses/6 weeks), then increase the dose to 1.33 mg/kg once every 3 weeks.
  • If patients show an insufficient response to the modified dose (1.33 mg/kg) and do not achieve a reduction in RBC transfusions after two treatments (2 doses/6 weeks), then increase the dose to 1.75 mg/kg once every 3 weeks.
  • Discontinue the treatment if patients show an insufficient response to the modified dose (1.75 mg/kg) and do not achieve a reduction in RBC transfusions after three treatments (3 doses/9 weeks).

Reblozyl Side Effects

The most common side effects of Reblozyl include:

  • Feeling tired
  • Muscle or bone pain
  • Pagkahilo
  • Pagtatae
  • Stomach (abdominal) pain
  • Mga reaksiyong alerdyi
  • Sakit ng ulo
  • Joint pain (arthralgia)
  • Pagduduwal
  • Ubo
  • Signs of a common cold
  • Flu-like signs

Some serious side effects that may occur include:

  • Blood clots (thrombosis/thromboembolism)
    • The risk may be greater in people who have had their spleen removed or who take birth control pills or hormone replacement therapy.
    • It is important to call your healthcare provider or get medical help immediately if you experience any of these symptoms:
      • Pananakit ng dibdib
      • Difficulty breathing or shortness of breath
      • Pain in your leg, with or without swelling
      • A pale or cold arm or leg
      • Sudden numbness or weakness that is short-term or continues to occur over an extended period of time, especially if it’s on one side of the body
      • Severe headache or confusion
      • Sudden dizziness or trouble with seeing, walking, speaking, or balancing
  • High blood pressure (hypertension)
    • Your provider will check your blood pressure before you receive your Reblozyl dose
  • Extramedullary hematopoietic (EMH) masses
    • It is important to call your healthcare provider or get medical help immediately if you experience any of these symptoms:
      • Severe back pain
      • Numbness, weakness, or loss of voluntary movement in the legs, arms, hands, or feet
      • Loss of bowel and bladder control

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