지원 작동 방식
비교할 수 없는 완벽한 편의성을 통해 환자의 전문 약국 경험을 간소화합니다.
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1. 보장 범위/혜택 확인
당사의 전문 청구자 팀은 실제 비용을 최소화하는 가장 적합한 보장 방안을 찾아드립니다.
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2. AmeriPharma®로 처방전 전송
우리는 귀하의 이전 약국이나 처방자와 협력하여 처방을 처리하므로 전환이 빠르고 쉽습니다.
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3. 사전 승인
저희 전문가 팀은 24~72시간 내에 귀하의 보험 회사로부터 승인을 받습니다.
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4. 공제금 지원 및 재정 지원
저희는 재정 지원을 확보하고 본인 부담금, 본인 부담금, 그리고 높은 공제액을 줄여드립니다. 현재까지 AmeriPharma® Specialty Care는 환자분들을 위해 1TP4억 4,700만 달러(약 1,447억 5,500만 원)의 재정 지원을 확보했습니다.
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5. 필요한 경우 간호 관리 조정
AmeriPharma®는 집에서 주입을 위해 전문 간호사 중 한 명과 일정을 조정하고 조정할 때 귀하의 일정과 가정 환경을 우선시합니다.
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6. 배송 조정
의약품은 항상 특정 배송 요건을 엄격히 준수하여 배송됩니다. 익일 배송 및 익일 배송은 고객님의 일정에 맞춰 조정됩니다.
What Is Mekinist?
Mekinist is a medication used to treat several types of cancer in patients who have one of two specific gene mutations that are called BRAF V600E and BRAF V600K. Mekinist works by inhibiting the MEK1 and MEK2 kinase enzymes’ activity. These enzymes normally promote the cells’ rapid reproduction. Mekinist also activates the BRAF pathway, which inhibits melanoma cell growth.
The generic name of Mekinist is trametinib. It is manufactured by Novartis and was first approved by the 식품의약국(FDA) in 2013.
Mekinist is currently only available as a brand-name medication, and it comes in oral tablets of 0.5 mg and 2 mg.
What is Mekinist Used For?
Mekinist is FDA approved for the treatment of several cancer types when patients have BRAF V600E or BRAF V600K mutations (the mutations have to be detected by an approved test for Mekinist treatment to be appropriate). Mekinist is used as follows:
- As a single agent: For the treatment of melanoma that cannot be surgically removed or that is metastatic. Mekinist should be used in patients with BRAF V600E or BRAF V600K mutations who have not been treated by a BRAF inhibitor before.
- In combination with Tafinlar (dabrafenib) for:
- Melanoma
- As an adjuvant treatment in patients with BRAF V600E or BRAF V600K mutations and lymph node involvement following complete surgical removal of the melanoma.
- For the treatment of melanoma that cannot be surgically removed or that is metastatic in patients with BRAF V600E mutation.
- Metastatic non-small cell lung cancer in patients with BRAF V600E or BRAF V600K mutations.
- Solid tumors that cannot be surgically removed or are metastatic in adult or pediatric patients (at least 6 years old) with BRAF V600E mutation whose tumors have progressed following prior treatment and who have no satisfactory alternative treatment options.
- Anaplastic thyroid cancer that is locally advanced or metastatic in patients with BRAF V600E mutation that have no satisfactory treatment options.
- Melanoma
Mekinist is NOT indicated for the treatment of colorectal cancer as it is known to have a resistance to BRAF inhibition.
공제금 및 재정 지원
AmeriPharma™ 전문 약국은 환자와 그 가족의 재정적 부담을 덜어줍니다.
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고급 소프트웨어는 귀하에게 최고 수준의 재단 프로그램을 매칭하기 위해 자금원을 찾아줍니다.
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당사의 공제금 지원 전문가 중 한 명이 신청 절차를 도와드립니다.
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자금 지원 상태에 대한 자동 업데이트가 귀하와 귀하의 의사에게 전송됩니다.
How To Take Mekinist
Upon confirmation of BRAF V600E or BRAF V600K mutations, Mekinist is taken as follows (please refer to the indicated use mentioned above for a full diagnosis description):
- Melanoma (as a single agent or in combination with Tafinlar): 2 mg once daily.
- Metastatic non-small cell lung cancer (in combination with Tafinlar): 2 mg once daily.
- Solid tumors that cannot be surgically removed or that are metastatic (in combination with Tafinlar): 2 mg once daily.
- Anaplastic thyroid cancer that is locally advanced or metastatic (in combination with Tafinlar): 2 mg once daily.
Mekinist should be taken at least 1 hour before or 2 hours after a meal. Doses should be taken about 24 hours apart, whether taken as a single agent or in combination with Tafinlar.
Missed doses should NOT be taken within 12 hours of the next dose.
If taken as a combination with Tafinlar, Mekinist should either be taken with the morning or evening dose of Tafinlar.
Mekinist Side Effects
- Edema/swelling (including peripheral edema to the limbs)
- High blood pressure (or worsening of existing high blood pressure)
- Outbreak of acne-like papules and pustules
- 발진
- Skin dryness
- Decrease in the serum albumin
- 복통
- 설사
- Mouth sores
- Anemia
- Bleeding
- Lymphedema (tissue swelling due to accumulation of protein-rich fluid)
- Increase in liver enzymes (ALT, ALP, and AST)
- Slow heart rate
- Bacterial skin infection
- Inflammation of hair follicles
- Infection around the nail
- Itching
- Altered taste
- Dry mouth
- 현기증
- Muscle breakdown (can be damaging to the kidneys)
- Blurred vision
- Dry eyes
- Interstitial lung disease
- Inflammation of lung tissue
Mekinist may also cause: Bleeding problems, inflammation or tears to the stomach or intestines, blood clots, heart problems, eye problems, lung or breathing problems, fever, serious skin reactions, and increased blood sugar.
These are not all of the possible side effects that may occur. If you have questions about side effects, call your doctor.
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