{"id":27103,"date":"2025-01-23T16:59:05","date_gmt":"2025-01-23T23:59:05","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=27103"},"modified":"2026-03-20T15:25:29","modified_gmt":"2026-03-20T22:25:29","slug":"ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/","title":{"rendered":"IgIV para la encefalomielitis diseminada aguda: c\u00f3mo esta terapia puede ayudar cuando otros tratamientos fallan"},"content":{"rendered":"\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\">IVIG<\/a> for acute disseminated encephalomyelitis (ADEM) is an effective second-line treatment when corticosteroids fall short, or patients cannot take them due to some medical conditions.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-6596517143262481e9397a7846ba83bc\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tAsk About IVIG Home Infusion\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#A_Quick_Overview_of_Acute_Disseminated_Encephalomyelitis\" >A Quick Overview of Acute Disseminated Encephalomyelitis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#How_Is_Acute_Disseminated_Encephalomyelitis_Managed\" >How Is Acute Disseminated Encephalomyelitis Managed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#IVIG_for_Acute_Disseminated_Encephalomyelitis_How_Does_It_Work\" >IVIG for Acute Disseminated Encephalomyelitis: How Does It Work?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#When_Should_You_Get_IVIG_for_Acute_Disseminated_Encephalomyelitis\" >When Should You Get IVIG for Acute Disseminated Encephalomyelitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#IVIG_for_Disseminated_Encephalomyelitis_How_Effective_Is_It\" >IVIG for Disseminated Encephalomyelitis: How Effective Is It?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#Combining_Corticosteroids_and_IVIG\" >Combining Corticosteroids and IVIG<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#Other_Second-Line_Treatments\" >Other Second-Line Treatments<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#The_Challenges_of_Using_IVIG_for_Acute_Disseminating_Encephalomyelitis\" >The Challenges of Using IVIG for Acute Disseminating Encephalomyelitis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#Plasma_Exchange_vs_IVIG_for_Acute_Disseminating_Encephalomyelitis\" >Plasma Exchange vs. IVIG for Acute Disseminating Encephalomyelitis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-acute-disseminated-encephalomyelitis-how-this-therapy-can-help-when-other-treatments-fail\/#Frequently_Asked_Questions\" >Frequently Asked Questions<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\" id=\"h-a-quick-overview-of-acute-disseminated-encephalomyelitis\"><span class=\"ez-toc-section\" id=\"A_Quick_Overview_of_Acute_Disseminated_Encephalomyelitis\"><\/span>A Quick Overview of Acute Disseminated Encephalomyelitis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Acute disseminated encephalomyelitis (ADEM) is a sudden and severe autoimmune disorder. It causes damage to the protective coating surrounding nerve fibers.&nbsp;<\/p>\n\n\n\n<p>The process in which the immune system damages the coating is known as demyelination. In people with ADEM, demyelination occurs in the brain and spinal cord. Rarely, the optic nerves (carrying signals from the retina of the eyes to the brain) may be affected.&nbsp;<\/p>\n\n\n\n<p>Demyelination typically occurs after a bacterial or viral infection. Children are more likely than adults to get this condition.&nbsp;<\/p>\n\n\n\n<p>ADEM is a rare condition. The National Organization of Rare Disorders (NORD)<em> <\/em>estimates 0.07 to 0.09 new cases per 100,000 children [<a href=\"https:\/\/rarediseases.org\/rare-diseases\/acute-disseminated-encephalomyelitis\/\">1<\/a>]. The number of new cases in the general population is unknown.&nbsp;&nbsp;<\/p>\n\n\n\n<p>Another name for this condition is post-infectious encephalomyelitis.<\/p>\n\n\n\n<p>ADEM isn\u2019t inherited, but genetic factors may make you more likely to get it.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-how-is-acute-disseminated-encephalomyelitis-managed\"><span class=\"ez-toc-section\" id=\"How_Is_Acute_Disseminated_Encephalomyelitis_Managed\"><\/span>How Is Acute Disseminated Encephalomyelitis Managed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>There\u2019s no universally accepted treatment for ADEM, and the <a href=\"https:\/\/www.fda.gov\/\">U.S. FDA<\/a> hasn\u2019t approved any specific therapy to treat it.&nbsp;<\/p>\n\n\n\n<p>Your healthcare provider will typically start with high-dose intravenous corticosteroids and supportive care. Corticosteroids (the first-line treatment) can help reduce inflammation of the brain and spinal cord.&nbsp;<\/p>\n\n\n\n<p>Supportive care can include [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3152158\/\">2<\/a>]:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Measures to manage airway (some patients may need a machine to breathe)<\/li>\n\n\n\n<li>Antibiotics to help fight infections<\/li>\n\n\n\n<li>Antiseizure medications<\/li>\n\n\n\n<li>Maintenance of fluid and electrolyte balance<\/li>\n\n\n\n<li>Medications to prevent blood clots in the leg<\/li>\n<\/ul>\n\n\n\n<p>When corticosteroids don\u2019t work as desired, your healthcare provider will treat you with either plasma exchange (plasmapheresis) or IVIG.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-ivig-for-acute-disseminated-encephalomyelitis-how-does-it-work\"><span class=\"ez-toc-section\" id=\"IVIG_for_Acute_Disseminated_Encephalomyelitis_How_Does_It_Work\"><\/span>IVIG for Acute Disseminated Encephalomyelitis: How Does It Work?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>The exact mechanism is unknown. Health experts believe that IVIG may work in ADEM by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Decreasing the production of proteins (<a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/immunoglobulins-ig\/\">immunoglobulins<\/a> or antibodies) that damage the brain and spinal cord<\/li>\n\n\n\n<li>Accelerating the breakdown of immunoglobulins<\/li>\n\n\n\n<li>Preventing the immune system from forming harmful immune complexes (the binding of antibodies with disease-causing particles)<\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-324623650fbe84e54d8f95913b20ee36\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Financial Assistance for IVIG\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-when-should-you-get-ivig-for-acute-disseminated-encephalomyelitis\"><span class=\"ez-toc-section\" id=\"When_Should_You_Get_IVIG_for_Acute_Disseminated_Encephalomyelitis\"><\/span>When Should You Get IVIG for Acute Disseminated Encephalomyelitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>IVIG isn\u2019t the primary treatment for ADEM and may only be considered under certain conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>When intravenous corticosteroids fail to manage ADEM symptoms<\/li>\n\n\n\n<li>When some patients cannot tolerate high-dose corticosteroids due to certain medical conditions<\/li>\n\n\n\n<li>When corticosteroids might worsen the condition in ADEM patients who also have meningoencephalitis (inflammation of the brain and its coverings)<\/li>\n\n\n\n<li>When plasma exchange (a second-line treatment) doesn\u2019t work<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-ivig-for-disseminated-encephalomyelitis-how-effective-is-it\"><span class=\"ez-toc-section\" id=\"IVIG_for_Disseminated_Encephalomyelitis_How_Effective_Is_It\"><\/span>IVIG for Disseminated Encephalomyelitis: How Effective Is It?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home.jpg\" alt=\"Man on bed at home receiving IVIG therapy\" class=\"wp-image-27106\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/01\/ivig-at-home-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>Several case reports suggest IVIG can be an effective alternative to corticosteroids.&nbsp;<\/p>\n\n\n\n<p>For example, in a 1995 case report, investigators described an 11-year-old boy with ADEM who responded within 24 hours to IVIG. The patient received 400 mg\/kg IVIG daily for 5 days [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8576561\/\">3<\/a>].<\/p>\n\n\n\n<p>In addition, a 1999 study reported full recovery in two children (both younger than 10) who received 2 g\/kg IVIG for 5 days [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10429012\/\">4<\/a>].<\/p>\n\n\n\n<p>Similarly, a 2019 case study reported a 30-year-old female who fully recovered after prompt treatment with high-dose corticosteroid and IVIG. The patient received 0.4 g\/kg IVIG for 7 days [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6629195\/\">5<\/a>].<\/p>\n\n\n\n<p>According to the Australian National Blood Authority guidelines, which reviewed multiple case reports, second-line IVIG treatment can result in complete recovery in [<a href=\"https:\/\/www.criteria.blood.gov.au\/MedicalCondition\/View\/2611#\">6<\/a>]:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Children with monophasic ADEM (occurring once in a lifetime)<\/li>\n\n\n\n<li>Children with recurrent ADEM (more than one episode of the disease)<\/li>\n\n\n\n<li>Children with relapsing ADEM originally treated with IVIG within the previous six months<\/li>\n<\/ul>\n\n\n\n<p>The Canadian guidelines recommend IVIG for acute disseminating encephalomyelitis when steroid therapy fails. The IVIG doses mentioned in the guidelines are as follows [<a href=\"https:\/\/www.ihe.ca\/public\/uploaded\/Prairie%20Ig%20Final%20Guideline%2009.02.22.pdf\">7<\/a>]:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Induction<\/strong>: 2 g\/kg adjusted body weight divided over 2 to 5 days<\/li>\n\n\n\n<li><strong>Maintenance<\/strong> (for recurrent ADEM only): 0.4 to 2 g\/kg adjusted body weight every 4 to 6 weeks<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-combining-corticosteroids-and-ivig\"><span class=\"ez-toc-section\" id=\"Combining_Corticosteroids_and_IVIG\"><\/span>Combining Corticosteroids and IVIG<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Only in severe cases, a healthcare provider may recommend the combination of corticosteroids and IVIG. However, it\u2019s unclear if doing so has any added advantage.&nbsp;<\/p>\n\n\n\n<p>There have also been reports of healthcare providers administering plasma exchange with high-dose corticosteroids in severe cases of ADEM.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-other-second-line-treatments\"><span class=\"ez-toc-section\" id=\"Other_Second-Line_Treatments\"><\/span>Other Second-Line Treatments<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Patients with severe or steroid-resistant ADEM may receive other second-line treatments like <a href=\"https:\/\/ameripharmaspecialty.com\/discontinued\/cyclophosphamide\/\">cyclophosphamide<\/a> or <a href=\"https:\/\/ameripharmaspecialty.com\/cancer\/rituximab-rituxan\/\">rituximab<\/a>.\u00a0<\/p>\n\n\n\n<div  id=\"call-to-action-c92d441d6d7145b3500779aef6c8fb8f\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAbout Copay Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-the-challenges-of-using-ivig-for-acute-disseminating-encephalomyelitis\"><span class=\"ez-toc-section\" id=\"The_Challenges_of_Using_IVIG_for_Acute_Disseminating_Encephalomyelitis\"><\/span>The Challenges of Using IVIG for Acute Disseminating Encephalomyelitis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Despite promising results in initial small studies, several challenges still limit IVIG use for acute disseminating encephalomyelitis, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A lack of large, controlled human trials<\/li>\n\n\n\n<li>Timing of therapy (whether to start IVIG immediately or wait for corticosteroids to fail)<\/li>\n\n\n\n<li>Dosing guidelines<\/li>\n<\/ul>\n\n\n\n<p>While early findings suggest IVIG can enhance the pace of initial recovery, it\u2019s unknown whether IVIG can affect the time to or extent of full recovery.&nbsp;<\/p>\n\n\n\n<p>Other factors that can limit the use of IVIG for acute disseminating encephalomyelitis include the high <a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/cost-of-ivig-treatment\/\">cost of IVIG therapy<\/a> and access to IVIG.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-plasma-exchange-vs-ivig-for-acute-disseminating-encephalomyelitis\"><span class=\"ez-toc-section\" id=\"Plasma_Exchange_vs_IVIG_for_Acute_Disseminating_Encephalomyelitis\"><\/span>Plasma Exchange vs. IVIG for Acute Disseminating Encephalomyelitis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Both <a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig-vs-plasmapheresis\/\">plasma exchange and IVIG<\/a> are effective second-line treatments. Yet plasma exchange is often considered superior.&nbsp;<\/p>\n\n\n\n<p>Plasma exchange may pose fewer risks and a reduced rate of complications. Additionally, it is oftentimes more cost-effective for the patient.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-frequently-asked-questions\"><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions\"><\/span>Frequently Asked Questions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-how-do-you-treat-acute-disseminated-encephalomyelitis\">How do you treat acute disseminated encephalomyelitis?<\/h4>\n\n\n\n<p>Several treatment options for acute disseminated encephalomyelitis are available. These include high-dose intravenous corticosteroids, IVIG, and plasma exchange.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-what-is-the-first-line-treatment-for-adem\">What is the first-line treatment for ADEM?<\/h4>\n\n\n\n<p>High-dose intravenous corticosteroids are the first-line therapy for ADEM.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-what-is-the-protocol-for-adem-treatment\">What is the protocol for ADEM treatment?<\/h4>\n\n\n\n<p>The standard protocol of corticosteroid treatment for ADEM is intravenous methylprednisolone at 20 \u2013 30 mg\/kg\/day (maximum 1 g\/day) for 3 to 5 days, followed by tapering (gradually lowering the dosage) with oral prednisone for 4 to 6 weeks.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La IgIV para la encefalomielitis diseminada aguda (ADEM) es un tratamiento de segunda l\u00ednea eficaz cuando los corticosteroides son insuficientes o los pacientes no pueden tomarlos debido a alguna afecci\u00f3n m\u00e9dica. La encefalomielitis diseminada aguda (ADEM) es un trastorno autoinmune repentino y grave.<\/p>","protected":false},"author":27,"featured_media":27104,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[7],"tags":[33],"class_list":["post-27103","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ivig","tag-dr-samantha-kaeberlein"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IVIG for Acute Disseminated Encephalomyelitis: How This Therapy Can Help When Other Treatments Fail<\/title>\n<meta name=\"description\" content=\"Learn how IVIG can be used to treat acute disseminated encephalomyelitis. 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