{"id":26730,"date":"2024-10-31T11:24:30","date_gmt":"2024-10-31T18:24:30","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=26730"},"modified":"2026-03-20T14:56:23","modified_gmt":"2026-03-20T21:56:23","slug":"ivig-for-solid-organ-transplantation","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-solid-organ-transplantation\/","title":{"rendered":"IgIV para el trasplante de \u00f3rganos s\u00f3lidos"},"content":{"rendered":"\n<p>Solid organ transplantation is a surgical procedure that replaces a person\u2019s failing organ with a healthy one from a donor. It is a vital procedure that can benefit people who are suffering from severe organ failure.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-0191998bfa32be2b355d24f337a7281b\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tAsk About IVIG Home Infusion\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p>However, there are several challenges of solid organ transplantation. One challenge that patients often face is organ rejection. This happens when the body\u2019s immune system misidentifies the new organ as a foreign, harmful object and attacks it. To prevent this, doctors use immunosuppressant drugs that weaken their immune system, but this will also increase the risk of infection [<a href=\"https:\/\/atm.amegroups.org\/article\/view\/21898\/21469\">1<\/a>].<\/p>\n\n\n\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/ivig\/\">Intravenous Immunoglobulin (IVIG)<\/a> can help prevent transplant rejection. In this article, we will discuss IVIG and how it can enhance your chances of successful organ transplantation.<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-solid-organ-transplantation\/#What_Is_IVIG\" >What Is IVIG?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-solid-organ-transplantation\/#What_Are_the_Benefits_of_IVIG_for_Solid_Organ_Transplantation\" >What Are the Benefits of IVIG for Solid Organ Transplantation?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-solid-organ-transplantation\/#Role_of_IVIG_Before_Organ_Transplantation\" >Role of IVIG Before Organ Transplantation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-solid-organ-transplantation\/#Role_of_IVIG_After_Organ_Transplantation\" >Role of IVIG After Organ Transplantation<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/es\/ivig\/ivig-for-solid-organ-transplantation\/#The_Bottom_Line\" >The Bottom Line<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_IVIG\"><\/span><strong>What Is IVIG?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Intravenous Immunoglobulin (IVIG) is a treatment made from the plasma of thousands of donors, containing many different antibodies. IVIG can help you fight infections if you have a weakened immune system. It is used in various immune system disorders and inflammatory diseases like <a href=\"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/kawasaki-disease-10-frequently-asked-questions-answered\/\">Kawasaki disease<\/a>, lupus, and <a href=\"https:\/\/ameripharmaspecialty.com\/guillain-barre-syndrome\/gbs-guillain-barre-syndrome\/\">guillain-barre syndrome<\/a>.&nbsp;<\/p>\n\n\n\n<p>There are many benefits of IVIG for solid organ transplantation. IVIG can calm an overactive immune system, thus reducing the chance of organ rejection. Before and after surgery, you must take immunosuppressant drugs, which weakens your immune system. This makes you more prone to infections, and IVIG can help you fight these infections. In short, IVIG can make your transplant more successful and keep you healthier.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Are_the_Benefits_of_IVIG_for_Solid_Organ_Transplantation\"><\/span><strong>What Are the Benefits of IVIG for Solid Organ Transplantation?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Intravenous Immunoglobulin (IVIG) is a good supporting treatment option for solid organ transplantation. It can play a vital role in both the preparation of an organ transplant and management of the potential complications that come after the transplant. Below, we will discuss how IVIG can help you in different stages of organ transplantation.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Role_of_IVIG_Before_Organ_Transplantation\"><\/span><strong>Role of IVIG Before Organ Transplantation<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"291\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies.jpg\" alt=\"3D illustration of antibodies on a blue cell background\" class=\"wp-image-26733\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies-300x208.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies-86x60.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies-167x116.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies-280x194.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/10\/antibodies-370x256.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>Before solid organ transplantation, doctors primarily use intravenous immunoglobulin (IVIG) for desensitization. Desensitization is a medical process that reduces antibodies in a patient\u2019s blood that could harm a transplanted organ. You need to go through this process before organ transplantation if you have high levels of alloantibodies, which are antibodies that target transplanted organs. The higher the levels of alloantibodies present in your blood, the longer you have to wait before conducting surgery.&nbsp;<\/p>\n\n\n\n<p>In the past two decades, doctors have used IVIG as a tool for the desensitization process in kidney transplantation. It can reduce the alloantibody levels in your body, which can increase your chance of a successful organ transplant [<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/6804678\">2<\/a>][<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S088779630900090X?via%3Dihub\">5<\/a>]. For the desensitization process, doctors use IVIG alone or in combination with other treatments like steroids, plasma exchange, and immunosuppressive drugs like <a href=\"https:\/\/ameripharmaspecialty.com\/cancer\/rituximab-rituxan\/\">rituximab<\/a> [<a href=\"https:\/\/www.frontiersin.org\/journals\/immunology\/articles\/10.3389\/fimmu.2023.1223567\/full\">3<\/a>][<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S088779630900090X?via%3Dihub\">5<\/a>].&nbsp;<\/p>\n\n\n\n<p>Most of the documented success of IVIG in the desensitization process has been in kidney transplants. According to one study, there is a lack of evidence to support the use of IVIG for the desensitization process in heart, lung, and liver transplants [<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S088779630900090X?via%3Dihub\">5<\/a>]. However, a recent Canadian study suggested that the combined use of IVIG, plasma exchange, anti-thymocyte globulin, and <a href=\"https:\/\/ameripharmaspecialty.com\/discontinued\/myfortic-mycophenolic-acid\/\">mycophenolic acid<\/a> can benefit patients who have high levels of alloantibodies during lung transplants [<a href=\"https:\/\/www.amjtransplant.org\/article\/S1600-6135(22)00062-4\/fulltext\">4<\/a>].<\/p>\n\n\n\n<div  id=\"call-to-action-0b7a14d881c113a9fe3d85cb1a17cadf\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet IVIG Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Learn More<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Role_of_IVIG_After_Organ_Transplantation\"><\/span><strong>Role of IVIG After Organ Transplantation<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>After the organ transplantation, the primary concern is to prevent organ rejection. You may experience organ rejection within the first few months or after a long time. The rejection may be caused by cells or antibodies. If antibodies cause the rejection, then it is called antibody-mediated rejection (AMR). If doctors suspect AMR, they will implement a treatment regimen to suppress your immune system and save the transplanted organ.<\/p>\n\n\n\n<p>Various studies over the past decades have shown that using IVIG in combination with drugs like rituximab can lower your risk of organ rejection in kidney transplants [<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/6872046\">7<\/a>][<a href=\"https:\/\/www.amjtransplant.org\/article\/S1600-6135(22)07578-5\/fulltext\">8<\/a>]. It is also beneficial in treating AMR in other transplants like lung, heart, and liver [<a href=\"https:\/\/www.criteria.blood.gov.au\/MedicalCondition\/View\/2484\">9<\/a>].<\/p>\n\n\n\n<p>There is another notable complication that comes after your organ transplant. Many patients experience low levels of <a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/immunoglobulins-ig\/\">immunoglobulins<\/a> due to the use of immunosuppressants [<a href=\"https:\/\/www.jacionline.org\/article\/S0091-6749(16)31141-1\/fulltext\">10<\/a>]. This can make you more prone to infections. In this case, IVIG therapy can help you replenish immunoglobulin levels and protect you against infections. According to one study, the usage of IVIG can reduce your risk of getting infections after an organ transplant [<a href=\"https:\/\/journals.lww.com\/transplantjournal\/abstract\/2018\/07001\/intravenous_immunoglobulin_replacement_therapy_in.139.aspx\">11<\/a>].<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_Bottom_Line\"><\/span><strong>The Bottom Line<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>For over a decade, IVIG has been very useful in solid organ transplantation. It can ensure the long-term survival of a transplant recipient by lowering the alloantibody levels, preventing AMR (antibody-mediated rejection), and managing infections. However, we still need more research to understand the full potential of IVIG for solid organ transplantation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El trasplante de \u00f3rgano s\u00f3lido es un procedimiento quir\u00fargico que reemplaza el \u00f3rgano da\u00f1ado de una persona por uno sano de un donante. Es un procedimiento vital que puede beneficiar a quienes sufren una insuficiencia org\u00e1nica grave.\u00a0<\/p>","protected":false},"author":7,"featured_media":26731,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[7],"tags":[8],"class_list":["post-26730","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ivig","tag-dr-christine-leduc"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IVIG for Solid Organ Transplantation - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"This article discusses how IVIG can improve the chances of successful organ transplantation. 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She attended college at Midwestern University, where she graduated cum laude. The most rewarding part of her job is suggesting lifestyle changes, educating patients on how their medication works, and precepting future pharmacists. Her areas of expertise are customer service and knowledge of specialty medication. Having worked in the service industry in the past, she has gained the customer service skills necessary to understand the needs of her patients. Dr. Leduc is currently precepting students from Marshall B. Ketchum University, University of Kansas, and Midwestern University. In her free time, she enjoys traveling, baking, and gardening. 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