{"id":26475,"date":"2024-08-27T15:29:11","date_gmt":"2024-08-27T22:29:11","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=26475"},"modified":"2024-08-27T15:29:14","modified_gmt":"2024-08-27T22:29:14","slug":"hemophilia-and-aging-how-the-condition-affects-the-elderly-population","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/","title":{"rendered":"Hemofilia y envejecimiento: c\u00f3mo afecta la enfermedad a la poblaci\u00f3n de edad avanzada"},"content":{"rendered":"\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/classic-hemophilia-types-symptoms-treatment\/\">Hemophilia<\/a> is a rare genetic disease in which your blood doesn\u2019t clot properly. As a result, when you bleed, it can take a really long time to slow down the bleeding, and it might not even stop. This disease is usually seen in younger people because it starts in early life. There was a time when the lifespan of a hemophilia patient was short. But things have changed. With the advancement of modern medicine, people with hemophilia can now live much longer. However, with growing age, there come some complications. In this article, we are going to discuss hemophilia and aging, and the complications of hemophilia in elderly people.<\/p>\n\n\n\n<div  id=\"call-to-action-b5f67f4a81d67464072d6b9e3e2f7be9\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAbout Copay Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#What_Is_Hemophilia\" >What Is Hemophilia?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#Hemophilia_and_Aging\" >Hemophilia and Aging<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#1_Viral_Disease\" >1. Viral Disease<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#2_Development_of_Inhibitors\" >2. Development of Inhibitors<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#3_Heart-Related_Complications\" >3. Heart-Related Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#4_Cancer\" >4. Cancer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#5_Joint_Disease\" >5. Joint Disease<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#6_Managing_Multiple_Medications_and_Drug_Interactions\" >6. Managing Multiple Medications and Drug Interactions<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/es\/hemophilia\/hemophilia-and-aging-how-the-condition-affects-the-elderly-population\/#Hemophilia_and_Aging_The_Bottom_Line\" >Hemophilia and Aging: The Bottom Line<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Hemophilia\"><\/span><strong>What Is Hemophilia?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Hemophilia is a rare genetic disorder that\u2019s typically more common in males. People with hemophilia aren\u2019t able to form blood clots because they\u2019re missing certain proteins called clotting factors. These clotting factors are needed for the steps of blood clot formation. There are two main types of hemophilia: <a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/hemophilia-a-vs-b-whats-the-difference\/\">hemophilia A and hemophilia B<\/a>. Hemophilia A is caused by a lack of clotting factor VIII, and hemophilia B is caused by a lack of clotting factor IX. Both types of hemophilia lead to longer bleeding times, which harms joints and muscles over time. People with hemophilia often experience symptoms like joint pain, swelling, and headaches. They may also bleed internally and have trouble moving. They must manage these symptoms for the rest of their lives with medications that replace the missing clotting factors to help prevent or control bleeding episodes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hemophilia_and_Aging\"><\/span><strong>Hemophilia and Aging<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>With the advancement in the medical sector, the life expectancy for people with hemophilia has improved a lot. In 1920, the life expectancy of hemophilia patients was just 11.4 years. This has now increased to nearly a normal lifespan today [<a href=\"https:\/\/www.hemophilia.org\/sites\/default\/files\/document\/files\/nurses-guide-chapter-17-aging.pdf\">1<\/a>]. According to a 2011 report from the CDC, there are 18,270 people in the U.S. with hemophilia. Of these people, 2,278 (or 13%) are between 45 and 64 years old, and 530 (or 3%) are 65 years or older. The number of people with hemophilia who are over 65 is expected to grow a lot in the next decade. But living longer brings new challenges. The natural aging process can make hemophilia complications worse. Here are some of those complications:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_Viral_Disease\"><\/span><strong>1. Viral Disease<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Many viral infections, like hepatitis B, hepatitis C, and HIV, create great challenges for older hemophilia patients. The introduction of a therapy known as HAART has improved the survival of HIV-positive hemophilia patients. But, many people also have hepatitis B and C, especially those born before 1975 [<a href=\"https:\/\/ashpublications.org\/hematology\/article\/2010\/1\/191\/96370\/The-Aging-Patient-with-Hemophilia-Complications\">2<\/a>]. This is because hemophilia patients need some blood products, and back then, there was a lack of safety measures. Hepatitis B and C can cause severe liver disease, liver failure, and liver cancer. These conditions are difficult to manage, especially in old age. Furthermore, liver damage from these viral infections increases the risk of bleeding complications. This can make treatment more complex and reduce overall life expectancy.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_Development_of_Inhibitors\"><\/span><strong>2. Development of Inhibitors<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Inhibitors are antibodies (proteins) that your body creates against the treatment you receive. In the case of hemophilia, your body can develop inhibitors against factor VIII or factor IX therapy. These inhibitors can reduce your treatment\u2019s effectiveness, which can lead to hemophilia symptoms coming back, such as bleeding, joint damage, and pain. Inhibitors develop in about 30% of hemophilia A and 5% of hemophilia B patients, often within their first 20 \u2013 50 treatments. The risk of developing inhibitors increases with age and repeated treatments. By age 75, about 12% of people with mild or moderate hemophilia may have inhibitors [<a href=\"https:\/\/eprints.whiterose.ac.uk\/139926\/3\/BJHaem%20review%20Final%20PDF.pdf\">3<\/a>]. So, as you age, managing inhibitors may require special treatments and therapies.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop.jpg\" alt=\"Hands holding blood drop,\" class=\"wp-image-26478\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/blood-drop-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_Heart-Related_Complications\"><\/span><strong>3. Heart-Related Complications<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>The good news for hemophilia patients is that hemophilia may lower the risk of heart disease due to reduced blood clotting. A European study has shown that heart disease-related deaths are lower in men with hemophilia [<a href=\"https:\/\/doi.org\/10.1111\/hae.12445\">4<\/a>]. Despite this, age, high blood pressure, diabetes, and high cholesterol still pose heart risks. If an elderly hemophilia patient develops heart problems, then managing it becomes difficult, especially with surgeries and blood thinners, which increase bleeding risk [<a href=\"https:\/\/eprints.whiterose.ac.uk\/139926\/3\/BJHaem%20review%20Final%20PDF.pdf\">3<\/a>].<\/p>\n\n\n\n<div  id=\"call-to-action-17874b951ff77b2ede6580a928049d10\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Financial Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_Cancer\"><\/span><strong>4. Cancer<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Data suggests that older people with hemophilia are at a higher risk for certain cancers, including liver cancer and lymphoma. Liver cancer is a significant cause of death in people with hemophilia, especially in those over 45 or those who got hepatitis C at an older age [<a href=\"https:\/\/ashpublications.org\/hematology\/article\/2010\/1\/191\/96370\/The-Aging-Patient-with-Hemophilia-Complications\">2<\/a>]. So, for older people with hemophilia, regular checks are recommended to catch cancer early.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_Joint_Disease\"><\/span><strong>5. Joint Disease<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Repeated bleeding episodes over time in people with hemophilia can lead to long-term joint problems and joint disease, especially if there\u2019s bleeding into a joint. This is more serious in older patients and can cause significant pain. Moreover, managing pain is tough due to the risks associated with common painkillers. A common solution for managing pain is joint replacement surgery. However, bleeding management during surgery can be a challenge.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"6_Managing_Multiple_Medications_and_Drug_Interactions\"><\/span><strong>6. Managing Multiple Medications and Drug Interactions<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Older people often take multiple medications for various medical conditions. So, managing hemophilia in older people is complex because certain medications, including painkillers (e.g., NSAIDs like ibuprofen [Advil, Motrin]) and heart medications (e.g., aspirin, clopidogrel [Plavix]), can further raise the risk of bleeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hemophilia_and_Aging_The_Bottom_Line\"><\/span><strong>Hemophilia and Aging<\/strong>: <strong>The Bottom Line<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>As people with hemophilia age, they face new health challenges. They need treatment for their hemophilia and other conditions. For them, starting early treatment, getting regular checkups, and making personalized care plans are important. This can help them live a better life.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La hemofilia es una enfermedad gen\u00e9tica poco com\u00fan en la que la sangre no coagula correctamente. Como resultado, cuando sangra, puede tardar mucho tiempo en detenerse, e incluso puede que no se detenga.<\/p>","protected":false},"author":26,"featured_media":26477,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[6],"tags":[32],"class_list":["post-26475","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hemophilia","tag-dr-robert-hakim"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hemophilia and Aging: How the Condition Affects the Elderly Population<\/title>\n<meta name=\"description\" content=\"Learn about hemophilia and aging. 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