{"id":23274,"date":"2023-09-01T10:41:23","date_gmt":"2023-09-01T17:41:23","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=23274"},"modified":"2024-10-25T13:42:53","modified_gmt":"2024-10-25T20:42:53","slug":"metabolic-complications-of-tpn","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/","title":{"rendered":"Complicaciones metab\u00f3licas de TPN"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">TPN, tambi\u00e9n conocido como <a href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/tpn-solution\/a-complete-guide-to-tpn-therapy\/\">nutrici\u00f3n parenteral total<\/a>Es una terapia farmacol\u00f3gica intravenosa que se utiliza para personas con problemas digestivos o que no pueden ingerir alimentos por v\u00eda oral. TPN contiene una mezcla de diversos componentes para satisfacer las necesidades nutricionales o diet\u00e9ticas de una persona, incluyendo carbohidratos, prote\u00ednas, grasas, vitaminas, minerales y otros oligoelementos.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-4045e710c72d9de6ca6cb08086ce6b3c\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tFluidos intravenosos totalmente disponibles\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tDisponibilidad constante, atenci\u00f3n ininterrumpida\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Empezar<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><span style=\"font-weight: 400;\">Sin duda, el TPN es una terapia vital que suministra nutrientes directamente al torrente sangu\u00edneo. Sin embargo, dado que el m\u00e9todo de ingesta de alimentos y el proceso metab\u00f3lico cambian repentinamente debido al TPN, el cuerpo puede presentar algunas complicaciones como respuesta al cambio. La terapia con TPN debe usarse durante el menor tiempo posible y el cambio a... <a href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/enteral-vs-parenteral-nutrition-a-complete-guide\/\">terapia enteral (oral, sonda de alimentaci\u00f3n)<\/a> Debe realizarse tan pronto como el paciente pueda. En este blog, analizaremos las cuatro complicaciones metab\u00f3licas m\u00e1s comunes que pueden surgir con TPN y c\u00f3mo abordarlas o prevenirlas.&nbsp;<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabla de contenido\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Palanca<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/#What_Is_Meant_By_Metabolic_Complications_and_Why_They_Occur\" >\u00bfQu\u00e9 se entiende por complicaciones metab\u00f3licas y por qu\u00e9 ocurren?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/#Top_4_Metabolic_Complications_of_TPN_And_How_To_Prevent_Them\" >Las 4 principales complicaciones metab\u00f3licas de TPN y c\u00f3mo prevenirlas<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/#Hyperglycemia_high_blood_glucose\" >Hiperglucemia (nivel alto de glucosa en sangre)&nbsp;&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/#Electrolyte_Imbalance\" >Desequilibrio electrol\u00edtico<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/#Refeeding_Syndrome\" >S\u00edndrome de realimentaci\u00f3n&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/#Liver_Dysfunction\" >Disfunci\u00f3n hep\u00e1tica&nbsp;<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Meant_By_Metabolic_Complications_and_Why_They_Occur\"><\/span>\u00bfQu\u00e9 se entiende por complicaciones metab\u00f3licas y por qu\u00e9 ocurren?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">El metabolismo es la reacci\u00f3n qu\u00edmica que ocurre en nuestro cuerpo para convertir los nutrientes presentes en los alimentos en energ\u00eda. Cuando el metabolismo normal se altera por cualquier motivo, como una enfermedad, un tratamiento, una terapia farmacol\u00f3gica o cualquier otro factor externo, puede causar complicaciones, com\u00fanmente conocidas como complicaciones metab\u00f3licas.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Las complicaciones metab\u00f3licas suelen implicar desequilibrios o alteraciones en los niveles de electrolitos, hormonas, nutrientes y otras sustancias necesarias para diversas funciones corporales. Estos desequilibrios pueden provocar complicaciones metab\u00f3licas, como hiperglucemia y disfunci\u00f3n hep\u00e1tica. <a href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/what-is-refeeding-syndrome\/\">s\u00edndrome de realimentaci\u00f3n<\/a>, y desequilibrios electrol\u00edticos.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Top_4_Metabolic_Complications_of_TPN_And_How_To_Prevent_Them\"><\/span>Las 4 principales complicaciones metab\u00f3licas de TPN y c\u00f3mo prevenirlas<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Las 4 complicaciones metab\u00f3licas m\u00e1s comunes de TPN son:<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hyperglycemia_high_blood_glucose\"><\/span><span style=\"font-weight: 400;\">Hiperglucemia (nivel alto de glucosa en sangre)&nbsp;&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test.jpg\" alt=\"Scientist hold a sample tube of Glucose test to measure TPN metabolic complications. \" class=\"wp-image-23277\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/09\/glucose-test-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">La nutrici\u00f3n parenteral total se formula com\u00fanmente seg\u00fan las necesidades individuales del paciente. Como <a href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/what-is-in-a-tpn-solution\/\">Soluciones TPN<\/a> contienen glucosa, las formulaciones parenterales totales con mayores cantidades de glucosa pueden aumentar los niveles de az\u00facar en la sangre del paciente, provocando hiperglucemia.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Para prevenir o reducir el riesgo de hiperglucemia, es fundamental controlar la glucemia durante el tratamiento con TPN y usar formulaciones con niveles bajos o moderados de glucosa. Si se produce hiperglucemia por el uso de TPN, se puede tratar con ciertos medicamentos, como la insulina, para reducir los niveles de glucosa. Adem\u00e1s, es necesario controlar cuidadosamente los niveles de az\u00facar en los pacientes hasta su completa recuperaci\u00f3n.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Electrolyte_Imbalance\"><\/span><span style=\"font-weight: 400;\">Desequilibrio electrol\u00edtico<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Otra complicaci\u00f3n metab\u00f3lica y una preocupaci\u00f3n importante asociada con el uso de TPN es el desequilibrio electrol\u00edtico. La administraci\u00f3n de TPN puede alterar los niveles de electrolitos en el cuerpo, como calcio, sodio, magnesio y potasio, lo que puede provocar complicaciones adicionales, como <a href=\"https:\/\/www.nhlbi.nih.gov\/health\/arrhythmias#:~:text=An%20arrhythmia%2C%20or%20irregular%20heartbeat,down%20while%20resting%20or%20sleeping.\">arritmias<\/a>, disfunci\u00f3n neuromuscular y otras.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">La prevenci\u00f3n del desequilibrio electrol\u00edtico requiere una evaluaci\u00f3n estrecha de los niveles de electrolitos, un seguimiento regular y ajustes de dosis o formulaci\u00f3n seg\u00fan la condici\u00f3n del paciente con la colaboraci\u00f3n de m\u00e9dicos, farmac\u00e9uticos y nutricionistas.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-ee45a96aad45c0869b7516304ad2c676\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tHabla con un especialista\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAcerca de la asistencia para copagos\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Programar una consulta<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Refeeding_Syndrome\"><\/span><span style=\"font-weight: 400;\">S\u00edndrome de realimentaci\u00f3n&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">El s\u00edndrome de realimentaci\u00f3n es una afecci\u00f3n metab\u00f3lica que se produce cuando un paciente con desnutrici\u00f3n o privaci\u00f3n grave de nutrientes recibe una nutrici\u00f3n excesiva y r\u00e1pida, como en el caso de TPN u otras formas de terapia diet\u00e9tica. El s\u00edndrome de realimentaci\u00f3n causa desequilibrios electrol\u00edticos y deficiencias vitam\u00ednicas, y tambi\u00e9n puede provocar convulsiones, coma o incluso la muerte.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Por lo tanto, para prevenir el s\u00edndrome de realimentaci\u00f3n, es crucial adoptar un enfoque gradual en la terapia nutricional, principalmente en pacientes con desnutrici\u00f3n o privaci\u00f3n grave de nutrientes, as\u00ed como en personas que han seguido dietas extremas o ayuno. Antes de administrar TPN, el m\u00e9dico o farmac\u00e9utico debe preguntar sobre el historial m\u00e9dico del paciente para prevenir este tipo de situaciones.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Liver_Dysfunction\"><\/span><span style=\"font-weight: 400;\">Disfunci\u00f3n hep\u00e1tica&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">La disfunci\u00f3n hep\u00e1tica por TPN puede ocurrir como resultado de un desequilibrio de grasas (l\u00edpidos) y una infusi\u00f3n excesiva de glucosa o l\u00edpidos, lo que puede comprometer las funciones hep\u00e1ticas del paciente.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Para reducir el riesgo de disfunci\u00f3n hep\u00e1tica relacionada con TPN, los profesionales de la salud minimizan la administraci\u00f3n y formulaci\u00f3n excesiva de l\u00edpidos y glucosa en la terapia con TPN, y monitorizan cuidadosamente los niveles hep\u00e1ticos para garantizar que no se produzcan da\u00f1os. La transici\u00f3n a un enfoque de nutrici\u00f3n enteral ayudar\u00e1 a disminuir el riesgo de disfunci\u00f3n hep\u00e1tica en los pacientes.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>TPN, tambi\u00e9n conocido como nutrici\u00f3n parenteral total, es una terapia farmacol\u00f3gica intravenosa que se utiliza para personas con problemas del sistema digestivo (tracto gastrointestinal) o que no pueden ingerir alimentos por v\u00eda oral. TPN contiene una mezcla de diversos componentes para satisfacer las necesidades nutricionales o diet\u00e9ticas de una persona, incluyendo carbohidratos, prote\u00ednas, grasas, vitaminas, minerales y otros oligoelementos.\u00a0<\/p>","protected":false},"author":27,"featured_media":23276,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[12],"tags":[33],"class_list":["post-23274","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tpn","tag-dr-samantha-kaeberlein"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Metabolic Complications of TPN - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"This article answers the question, &quot;What are metabolic complications of TPN?&quot; Includes the top 4 complications and how to prevent them.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/es\/tpn\/metabolic-complications-of-tpn\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Metabolic Complications of TPN - 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