{"id":23155,"date":"2023-08-10T11:35:33","date_gmt":"2023-08-10T18:35:33","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=23155"},"modified":"2024-08-13T17:27:32","modified_gmt":"2024-08-14T00:27:32","slug":"jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/","title":{"rendered":"Jaypirca: El f\u00e1rmaco innovador para el linfoma de c\u00e9lulas del manto"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Como el primer inhibidor no covalente de la tirosina quinasa de Bruton (BTK) aprobado por la FDA para el tratamiento de reca\u00eddas o refractarios. <a href=\"https:\/\/lymphoma.org\/understanding-lymphoma\/aboutlymphoma\/nhl\/mantle-cell-lymphoma\/\">linfoma de c\u00e9lulas del manto<\/a> Jaypirca (pirtobrutinib), un medicamento innovador para el LCM, representa un avance significativo en la lucha contra este c\u00e1ncer de sangre poco com\u00fan y agresivo. Este medicamento innovador para el LCM ofrece nuevas esperanzas a los pacientes que han agotado otras opciones de tratamiento.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-d7db6fa887bbff54ff6d12d46f3f1413\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tHabla con un especialista\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAcerca de la asistencia para copagos\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><span style=\"font-weight: 400;\">Este art\u00edculo le brindar\u00e1 una revisi\u00f3n en profundidad del impacto de Jaypirca en el tratamiento del MCL, c\u00f3mo funciona, sus riesgos asociados y qu\u00e9 precauciones se deben tomar antes o durante el tratamiento.<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabla de contenido\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Palanca<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#What_Is_Jaypirca\" >\u00bfQu\u00e9 es Jaypirca?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#What_Is_Jaypirca_Used_To_Treat\" >\u00bfPara qu\u00e9 se utiliza Jaypirca?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#How_Does_Jaypirca_Work\" >\u00bfC\u00f3mo funciona Jaypirca?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Mode_of_Action\" >Modo de acci\u00f3n<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Jaypirca_Dosage_Form_and_Strength\" >Forma farmac\u00e9utica y concentraci\u00f3n de Jaypirca<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Dosing_Information\" >Informaci\u00f3n de dosificaci\u00f3n<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Overdose\" >Sobredosis&nbsp;<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#How_Is_Jaypirca_Used\" >\u00bfC\u00f3mo se utiliza Jaypirca?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Possible_Side_Effects\" >Posibles efectos secundarios<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#What_Drugs_Should_You_Avoid_While_Taking_Jaypirca\" >\u00bfQu\u00e9 medicamentos debes evitar mientras tomas Jaypirca?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Precaution_While_Taking_Jaypirca\" >Precauciones al tomar Jaypirca<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/es\/other-health-conditions\/jaypirca-the-breakthrough-drug-for-mantle-cell-lymphoma\/#Cost\" >Costo<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Jaypirca\"><\/span>\u00bfQu\u00e9 es Jaypirca?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca es un medicamento contra el c\u00e1ncer, tambi\u00e9n conocido por el nombre de su principio activo: pirtobrutinib. Este medicamento recibi\u00f3 recientemente la aprobaci\u00f3n acelerada de la FDA el 27 de enero de 2023 para el tratamiento del linfoma de c\u00e9lulas del manto (LCM) refractario o recidivante, un tipo de linfoma no Hodgkin (LNH), en pacientes adultos. Como medicamento de aprobaci\u00f3n acelerada, Jaypirca satisface una necesidad m\u00e9dica para el LCM que otras terapias farmacol\u00f3gicas actualmente no cubren. Sin embargo, para obtener la aprobaci\u00f3n regular de la FDA, la compa\u00f1\u00eda farmac\u00e9utica debe completar ensayos cl\u00ednicos para confirmar a\u00fan m\u00e1s el beneficio cl\u00ednico de este medicamento.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca (pirtobrutinib) pertenece a la clase de f\u00e1rmacos denominados &quot;inhibidores de BTK&quot;, que bloquean la actividad de la enzima BTK e inhiben el crecimiento anormal de c\u00e9lulas B en el LCM. Jaypirca es \u00fanico por ser un inhibidor no covalente, mientras que otros tratamientos para el LCM disponibles en el mercado son... <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7557570\/\">inhibidores covalentes<\/a>Como inhibidor no covalente, Jaypirca se dirige a mutaciones espec\u00edficas de BTK que se est\u00e1n volviendo resistentes a los inhibidores covalentes.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Jaypirca_Used_To_Treat\"><\/span>\u00bfPara qu\u00e9 se utiliza Jaypirca?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca se utiliza para tratar el linfoma de c\u00e9lulas del manto (LCM) refractario o recidivante en pacientes adultos cuyo c\u00e1ncer ha regresado o ha dejado de responder a tratamientos previos y que han recibido al menos dos o m\u00e1s terapias previas, incluidos medicamentos BTK covalentes.<\/span><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">El linfoma de c\u00e9lulas del manto (LCM) es un tipo de c\u00e1ncer de la sangre que afecta al sistema linf\u00e1tico y se cree que surge de mutaciones gen\u00e9ticas o cambios en los linfocitos B, un tipo de gl\u00f3bulo blanco que ayuda al cuerpo a combatir infecciones. En el LCM, estos cambios gen\u00e9ticos provocan que los linfocitos B crezcan y se dividan de forma descontrolada, lo que lleva a la formaci\u00f3n de una masa de c\u00e9lulas anormales (tumores) en el sistema linf\u00e1tico. El LCM suele desarrollarse en los ganglios linf\u00e1ticos, pero tambi\u00e9n puede propagarse a otros \u00f3rganos, como la m\u00e9dula \u00f3sea, el bazo y el tracto gastrointestinal.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">El MCL es un tipo relativamente raro de linfoma no Hodgkin (LNH) y representa aproximadamente el 61% de todos los casos de LNH.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_Jaypirca_Work\"><\/span>\u00bfC\u00f3mo funciona Jaypirca?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca contiene un principio activo, &quot;pirtobrutinib&quot;, que act\u00faa como inhibidor no covalente de BTK y bloquea la actividad de la enzima BTK. Esta enzima es un componente clave de la v\u00eda de se\u00f1alizaci\u00f3n del receptor de c\u00e9lulas B (BCR), esencial para el desarrollo y la funci\u00f3n de las c\u00e9lulas B, un tipo de gl\u00f3bulo blanco.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Generalmente, en el MCL, las c\u00e9lulas B cancerosas producen un exceso de enzimas BTK, lo que conduce al crecimiento y proliferaci\u00f3n descontrolados de estas c\u00e9lulas.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mode_of_Action\"><\/span><b>Modo de acci\u00f3n<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca inhibe reversiblemente la actividad de la enzima BTK, altera la v\u00eda de se\u00f1alizaci\u00f3n del BCR e interfiere con la activaci\u00f3n y proliferaci\u00f3n de linfocitos B. Esto reduce el n\u00famero de linfocitos B cancerosos y ralentiza la progresi\u00f3n de la enfermedad.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca es altamente selectivo para BTK y posee un perfil de uni\u00f3n \u00fanico que lo diferencia de otros inhibidores de BTK. Esta uni\u00f3n selectiva proporciona mayor eficacia y seguridad en el tratamiento del LCM.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Es importante se\u00f1alar que el mecanismo de acci\u00f3n exacto de Jaypirca en el tratamiento del MCL a\u00fan se est\u00e1 estudiando y se necesita m\u00e1s investigaci\u00f3n para comprender completamente los efectos del medicamento sobre las c\u00e9lulas B cancerosas.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Jaypirca_Dosage_Form_and_Strength\"><\/span>Forma farmac\u00e9utica y concentraci\u00f3n de Jaypirca<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Jaypirca est\u00e1 disponible actualmente en comprimidos de 50 mg y 100 mg. Jaypirca es bien tolerado y solo se vende con receta m\u00e9dica.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-5fc5c0f0f0c9b6af580c94f0df927d32\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tObtenga asistencia financiera para Jaypirca\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Programar una consulta<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosing_Information\"><\/span>Informaci\u00f3n de dosificaci\u00f3n<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">La dosis inicial recomendada para adultos con LCM es de 200 mg (dos comprimidos de 100 mg) una vez al d\u00eda. Sin embargo, la dosis de Jaypirca puede ajustarse seg\u00fan el estado de salud del paciente. Por ejemplo, si padece insuficiencia renal grave, toma ciertos medicamentos o experimenta una reacci\u00f3n adversa a su dosis actual de Jaypirca, su m\u00e9dico podr\u00eda ajustar la dosis para reducir los efectos secundarios.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Overdose\"><\/span><b>Sobredosis&nbsp;<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Evite tomar una dosis doble de Jaypirca para compensar la dosis olvidada. Si ha omitido su dosis por m\u00e1s de 12 horas, om\u00edtala y tome la siguiente dosis programada a la hora habitual que le haya recetado su m\u00e9dico.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Jaypirca_Used\"><\/span>\u00bfC\u00f3mo se utiliza Jaypirca?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">La tableta de Jaypirca se toma por v\u00eda oral (por la boca). Puede tomarla con o sin alimentos. La tableta debe tragarse, no masticarse, triturarse ni cortarse.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Possible_Side_Effects\"><\/span>Posibles efectos secundarios<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects.jpg\" alt=\"Man suffering from fatigue as a side effect of Jaypirca\" class=\"wp-image-23157\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/jaypirca-side-effects-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">Los posibles efectos secundarios comunes que se informan cl\u00ednicamente en \u2265 15% de pacientes con LCM despu\u00e9s de tomar Jaypirca incluyen:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Cansancio o fatiga<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Diarrea<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Neumon\u00eda<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dolor musculoesquel\u00e9tico (dolor muscular, \u00f3seo y articular)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Hinchaz\u00f3n y hematomas<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dificultad para respirar (disnea)<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Adem\u00e1s, las reacciones adversas menos comunes o raras incluyen:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Infecciones (incluidas infecciones bacterianas, virales o f\u00fangicas)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Problemas de sangrado (incluyendo sangre en la orina, las heces o v\u00f3mitos con sangre)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Disminuci\u00f3n del recuento de c\u00e9lulas sangu\u00edneas <\/span><span style=\"font-weight: 400;\">(<\/span><span style=\"font-weight: 400;\">incluyendo neutropenia, anemia y trombocitopenia)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.heart.org\/en\/health-topics\/atrial-fibrillation\/what-is-atrial-fibrillation-afib-or-af\">Fibrilaci\u00f3n auricular<\/a> y aleteo (latidos card\u00edacos anormales o malestar en el pecho)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Segundas neoplasias malignas primarias (nuevos c\u00e1nceres de la piel o de otros \u00f3rganos)<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Drugs_Should_You_Avoid_While_Taking_Jaypirca\"><\/span>\u00bfQu\u00e9 medicamentos debes evitar mientras tomas Jaypirca?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otros medicamentos pueden interactuar con Jaypirca y reducir su eficacia. Es importante informar a su m\u00e9dico sobre todos los medicamentos que est\u00e9 tomando, tanto los recetados como los de venta libre. Los siguientes son algunos de los medicamentos que, seg\u00fan se ha informado, pueden afectar el mecanismo de acci\u00f3n de Jaypirca y aumentar el riesgo de efectos secundarios:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Fuerte <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cyp3a#:~:text=CYP3A%20inducers%20include%20the%20glucocorticoids,ketoconazole%2C%20clarithromycin%2C%20and%20verapamil.\">Inhibidores del CYP3A<\/a> (itraconazol) <\/span><span style=\"font-weight: 400;\">y inductores (<\/span><span style=\"font-weight: 400;\">rifampicina y hierba de San Juan)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Inductores moderados del CYP3A (<\/span><span style=\"font-weight: 400;\">efavirenz y bosent\u00e1n) e inhibidores (verapamilo y diltiazem)<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precaution_While_Taking_Jaypirca\"><\/span>Precauciones al tomar Jaypirca<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">No tome Jaypirca si usted:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>Embarazada o planea quedar embarazada.<\/b><span style=\"font-weight: 400;\">&nbsp;Jaypirca puede causar da\u00f1o fetal, seg\u00fan estudios realizados en animales.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Amamantar o planea amamantar<\/b><span style=\"font-weight: 400;\">Dado que se desconoce si este medicamento se excreta en la leche materna, se recomienda evitar la lactancia materna mientras toma Jaypirca y durante una semana despu\u00e9s de su \u00faltima dosis.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Adem\u00e1s,<\/span> <span style=\"font-weight: 400;\">Informe a su proveedor de atenci\u00f3n m\u00e9dica si:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Tiene presi\u00f3n arterial alta&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tiene antecedentes de c\u00e1ncer<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tiene o ha tenido problemas del ritmo card\u00edaco<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tiene trastornos hemorr\u00e1gicos o est\u00e1 tomando anticoagulantes.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tiene problemas renales<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Se ha sometido a una cirug\u00eda recientemente o planea someterse a una cirug\u00eda.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tiene una infecci\u00f3n o es propenso a infecciones.<\/span><\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-3cf5b956cd4d2e81824b9ecdb6ef6f3d\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tObtenga asistencia para el copago de Jayprica\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tHabla con un especialista\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span>Costo<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">T<\/span><span style=\"font-weight: 400;\">\u00e9l <\/span><span style=\"font-weight: 400;\">El costo estimado de adquisici\u00f3n mayorista de Jaypirca en EE. UU. ser\u00e1 de $21,000 para un mes (30 d\u00edas) de terapia con una dosis diaria de 200 mg. Sin embargo, el precio oficial de distribuci\u00f3n estar\u00e1 disponible en EE. UU. m\u00e1s adelante. <\/span><span style=\"font-weight: 400;\">cuarto. <a href=\"https:\/\/ameripharmaspecialty.com\/es\/financial-assistance\/\">Cont\u00e1ctanos<\/a> Si usted est\u00e1 interesado en recibir ayuda financiera para Jaypirca.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Jaypirca se utiliza para tratar el linfoma de c\u00e9lulas del manto (LCM) refractario o recidivante en pacientes adultos cuyo c\u00e1ncer ha regresado o ha dejado de responder a tratamientos previos y que han recibido al menos dos o m\u00e1s terapias previas, incluidos medicamentos BTK covalentes.\u00a0<\/p>","protected":false},"author":27,"featured_media":23156,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[4],"tags":[33],"class_list":["post-23155","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other-health-conditions","tag-dr-samantha-kaeberlein"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Jaypirca: The Breakthrough Drug for Mantle Cell Lymphoma - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn about how Jaypirca treats mantle cell lymphoma. 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