{"id":19395,"date":"2022-03-16T12:45:37","date_gmt":"2022-03-16T19:45:37","guid":{"rendered":"https:\/\/ameripharmaspe.wpengine.com\/staging\/?p=18733"},"modified":"2026-03-20T15:16:17","modified_gmt":"2026-03-20T22:16:17","slug":"eligard-leuprolide-acetate","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/","title":{"rendered":"Eligard (acetato de leuprolida)"},"content":{"rendered":"\n<p>Eligard (leuprolide acetate) is a long-acting injectable hormone therapy used in the management of advanced prostate cancer. It works by suppressing testosterone production, a key driver of prostate cancer growth. This article reviews Eligard\u2019s indications, mechanism of action, dosing, benefits, risks, and available alternatives.<\/p>\n\n\n\n<p>Eligard is the brand name for leuprolide acetate, a long-acting subcutaneous injectable hormone therapy used in the palliative treatment of advanced prostate cancer.<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Eligard_Indications_Composition_and_Manufacturer\" >Eligard Indications, Composition, and Manufacturer<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#What_Is_Eligard_Used_For\" >What Is Eligard Used For?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Manufacturer\" >Manufacturer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Eligard_Composition\" >Eligard Composition<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Hormone_Therapy_in_Advanced_Prostate_Cancer\" >Hormone Therapy in Advanced Prostate Cancer<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Medical_Versus_Surgical_Castration\" >Medical Versus Surgical Castration<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Eligard_vs_Lupron\" >Eligard vs. Lupron<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Eligard_Mechanism_of_Action_in_Prostate_Cancer\" >Eligard Mechanism of Action in Prostate Cancer<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#How_the_Body_Produces_Testosterone\" >How the Body Produces Testosterone<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Eligard_Structure_and_Effects\" >Eligard Structure and Effects<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Other_Hormone_Therapies_in_Advanced_Prostate_Cancer\" >Other Hormone Therapies in Advanced Prostate Cancer<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#What_Are_Some_of_the_Side_Effects_of_Eligard\" >What Are Some of the Side Effects of Eligard?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Common_Side_Effects\" >Common Side Effects&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Transient_Side_Effects\" >Transient Side Effects&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Serious_Adverse_Effects\" >Serious Adverse Effects&nbsp;<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Eligard_Dose_in_Prostate_Cancer\" >Eligard Dose in Prostate Cancer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#What_Are_the_Benefits_of_Eligard_Therapy_in_Prostate_Cancer\" >What Are the Benefits of Eligard Therapy in Prostate Cancer?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#For_How_Long_Should_You_Take_Eligard_in_Prostate_Cancer\" >For How Long Should You Take Eligard in Prostate Cancer?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Cost\" >Cost<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/#Copay_Assistance\" >Copay Assistance<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Eligard_Indications_Composition_and_Manufacturer\"><\/span><span style=\"font-weight: 400;\">Eligard Indications, Composition, and Manufacturer<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Eligard_Used_For\"><\/span><span style=\"font-weight: 400;\">What Is Eligard Used For?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Eligard is a prescription-only injectable medication that is used in the palliative treatment of advanced prostate cancer. Advanced prostate cancer refers to both locally advanced (stage 3) prostate cancer and metastatic (stage 4) prostate cancer. Eligard is administered into the subcutaneous tissue, which is located directly beneath the skin.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-663f14f3235da2b48f0ddcba4a0b1746\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Manufacturer\"><\/span><span style=\"font-weight: 400;\">Manufacturer<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Eligard was approved by the <a href=\"https:\/\/www.fda.gov\/\">U.S. Food and Drug Administration<\/a> (FDA) in 2004 for the treatment of advanced prostate cancer.<\/span> <span style=\"font-weight: 400;\">Eligard is a global product that is marketed worldwide. It is manufactured and marketed by <\/span><a href=\"https:\/\/www.tolmar.com\/products\/eligard\"><span style=\"font-weight: 400;\">Tolmar Inc.<\/span><\/a><span style=\"font-weight: 400;\">, its inventor and developer.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Eligard_Composition\"><\/span><span style=\"font-weight: 400;\">Eligard Composition<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Eligard is a long-acting injectable suspension of leuprolide acetate, also known as leuprorelin. It helps in the palliative treatment of advanced prostate cancer by reducing testosterone levels in the body, which can significantly slow the growth of the prostate tumor.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Once an Eligard injection is administered to a patient, leuprolide acetate, the active ingredient in Eligard, is released slowly [1]. This slow release is possible because Eligard uses a specialized drug delivery system called <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\"><span style=\"font-weight: 400;\">Atrigel<\/span><\/a><span style=\"font-weight: 400;\"> [<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\">2<\/a>].<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hormone_Therapy_in_Advanced_Prostate_Cancer\"><\/span><span style=\"font-weight: 400;\">Hormone Therapy in Advanced Prostate Cancer<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Medical_Versus_Surgical_Castration\"><\/span><span style=\"font-weight: 400;\">Medical Versus Surgical Castration<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Reducing the male sex hormone testosterone helps stop the growth of prostate cancer cells. This is done via a process known as castration, which is a type of <\/span><a href=\"https:\/\/www.cancer.org\/cancer\/prostate-cancer\/treating\/hormone-therapy.html\"><span style=\"font-weight: 400;\">hormone therapy<\/span><\/a><span style=\"font-weight: 400;\"> that involves the removal of testicular function either surgically or medically. Surgical removal of the testicles is the simplest and least expensive method of castration. Because it is permanent, however, it is not preferable to most patients. Medical castration, on the other hand, is done by administering medications that block testosterone production. In exchange for keeping the testes intact, doses of these drugs must be repeated regularly for an indefinite period of time to maintain castration status.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Eligard_vs_Lupron\"><\/span><span style=\"font-weight: 400;\">Eligard vs. Lupron<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Both Eligard and Lupron Depot contain the same active drug, leuprolide acetate. They are both long-acting preparations that are designed to release the medication slowly over several months. The only difference is that Eligard is given subcutaneously, the layer just underneath the skin, while Lupron Depot is given intramuscularly. The decision to use one over the other depends on preference and insurance coverage. Both forms must be administered by trained healthcare professionals.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-94bdc9907708c703580ce7b7a6332a0d\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist About Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Consult a Chemo Specialist<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Eligard_Mechanism_of_Action_in_Prostate_Cancer\"><\/span><span style=\"font-weight: 400;\">Eligard Mechanism of Action in Prostate Cancer<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Androgens such as testosterone stimulate the growth of prostate cancer cells. Eligard works to reduce male hormones in the body to counteract this.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_the_Body_Produces_Testosterone\"><\/span><span style=\"font-weight: 400;\">How the Body Produces Testosterone<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Testosterone production is regulated by a hormonal signaling pathway involving three primary components: the hypothalamus, the pituitary gland, and the testes.<\/p>\n\n\n\n<p>The hypothalamus, located in the brain, releases gonadotropin-releasing hormone (GnRH), which stimulates the pituitary gland to secrete gonadotropins into the bloodstream. These gonadotropins include follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Among these, LH plays the primary role in signaling the testes to produce testosterone.<\/p>\n\n\n\n<p>When LH reaches the Leydig cells in the testes, it stimulates the conversion of cholesterol into testosterone through a series of enzymatic steps. Testosterone then circulates throughout the body, where it regulates male sexual development and supports the growth of prostate tissue, including prostate cancer cells.<\/p>\n\n\n\n<p>This process is tightly regulated by a negative feedback mechanism, in which circulating testosterone levels suppress further GnRH and LH release to maintain hormonal balance.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Eligard_Structure_and_Effects\"><\/span><span style=\"font-weight: 400;\">Eligard Structure and Effects<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">The hypothalamus releases GnRH in pulses mainly due to the negative feedback from the presence of sex hormones. This works with the pituitary gland because it deregulates the number of GnRH receptors as a result of stimulation in order to prevent the potential overproduction of gonadotropins. Eligard utilizes these mechanisms to achieve castration.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Leuprolide acetate is a GnRH analog. It binds to GnRH receptors on the pituitary gland, and it mimics the effect of the actual hormone. Therefore, when Eligard treatment is started for the first time, the body perceives it as a pulse of GnRH. This causes a transient, increased production of gonadotropins and testosterone in the first 2 to 4 weeks of treatment. Over time, however, with constant stimulation of the GnRH receptors, the pituitary gland becomes almost completely desensitized from GnRH, leading to an indirect blockade of gonadotropin production. Without LH, the testicles <\/span><a href=\"https:\/\/www.cancer.gov\/types\/prostate\/prostate-hormone-therapy-fact-sheet\"><span style=\"font-weight: 400;\">stop producing testosterone<\/span><\/a><span style=\"font-weight: 400;\">. As a result, the body achieves <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\"><span style=\"font-weight: 400;\">castrate levels of testosterone<\/span><\/a><span style=\"font-weight: 400;\"> (&lt;50 ng\/dl). This effect has been shown to maintain for up to seven years with Eligard therapy [<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\">2<\/a>].<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Other_Hormone_Therapies_in_Advanced_Prostate_Cancer\"><\/span><span style=\"font-weight: 400;\">Other Hormone Therapies in Advanced Prostate Cancer<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">There are several other ways to reduce testosterone levels in the body. The following medications work differently from Eligard, but they achieve the same general purpose of reducing androgen levels in the body to discourage prostate tumor growth:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>GnRH antagonists:<\/b> <b>Orgovyx (relugolix)<\/b> <b>and Firmagon (degarelix)<\/b><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Like Eligard, these medications bind to GnRH receptors on the pituitary gland. However, binding does not stimulate the production of gonadotropins. Instead, they bind for the purpose of directly blocking the effect of GnRH.<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>Xytiga (<a href=\"https:\/\/ameripharmaspecialty.com\/cancer\/abiraterone-acetate-zytiga-yonsa\/\">abiraterone<\/a>)<\/b><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">This medication blocks the activity of one of the main enzymes involved in testosterone biosynthesis.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Though to a much lesser degree than the testicles, the adrenal glands may also produce testosterone. Because the effects of Xytiga are not organ-specific, it may also block this source as well.<\/span><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Androgen receptor blockers:&nbsp;Xtandi (enzalutamide)<\/strong>,&nbsp;<strong>Erleada (apalutamide), and&nbsp;<\/strong><a href=\"https:\/\/ameripharmaspecialty.com\/cancer\/darolutamide-nubeqa\/\"><strong>Nubeqa (darolutamide)<\/strong><\/a>\n<ul class=\"wp-block-list\">\n<li>These medications bind to androgen receptors and prevent cells from responding to the presence of testosterone.<\/li>\n\n\n\n<li>An antiandrogen may be temporarily prescribed to help reduce the side effects associated with the transient rise in testosterone levels during the initial phase.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-94f8a279ad1fdfcc8c1051097af27254\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Financial Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Are_Some_of_the_Side_Effects_of_Eligard\"><\/span><span style=\"font-weight: 400;\">What Are Some of the Side Effects of Eligard?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Common_Side_Effects\"><\/span><span style=\"font-weight: 400;\">Common Side Effects&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">As with most therapies, Eligard treatment is not without side effects. The following is a list of some of the more common ones that a patient may experience [5]:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Injection site reactions such as transient burning, stinging, bruising, or swelling<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Weakness, numbness, unsteadiness<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Hot flashes, sweating<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Muscle pain<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nausea or vomiting<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dysuria<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Hair loss<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Decreased libido, erectile dysfunction<\/span><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Transient_Side_Effects\"><\/span><span style=\"font-weight: 400;\">Transient Side Effects&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">In the first 2 to 4 weeks of treatment, patients may experience a temporary aggravation of the symptoms associated with prostate cancer. This is due to the initial increase in testosterone levels at the early treatment phase [<a href=\"https:\/\/eligard.com\/\">6<\/a>]. During this time, patients may develop new symptoms or experience worsening of their existing ones, such as bone pain, urinary disruptions, and fatigue. Once the testosterone levels begin to drop, these symptoms gradually improve over time.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Serious_Adverse_Effects\"><\/span><span style=\"font-weight: 400;\">Serious Adverse Effects&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">There are some severe adverse effects of Eligard to consider. Patients taking Eligard may have an increased risk of developing the following complications, particularly with long-term therapy:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Cardiovascular: chest pain, heart attack, arrhythmia, stroke<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Endocrine: diabetes and other metabolic disorders, pituitary gland dysfunction (rare), gynecomastia<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Neurological: seizure<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Psychiatric: mania, depression<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Skeletal: thinning of bones, fractures<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Genitourinary: infertility, testicular shrinkage<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Although patients with predisposing factors are at greater risk<\/span> <span style=\"font-weight: 400;\">of encountering the above issues, those who are otherwise healthy may also develop them during Eligard therapy. Many of these complications gradually develop. There will likely be signs before they truly become problematic, either as onsets of new symptoms or from blood work. Therefore, it is very important to be transparent and maintain regular communication with the doctor while on this treatment.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Discontinuation of Eligard may be dependent on the severity of these potential adverse events. Eligard should not be used in patients who are allergic to any of its components.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-fe9b0693b294d18f7fc17096556231f5\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tConsult a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tGet Treatment Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Eligard_Dose_in_Prostate_Cancer\"><\/span><span style=\"font-weight: 400;\">Eligard Dose in Prostate Cancer<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\">Eligard is available in 4 different doses<\/a>: 7.5 mg, 22.5 mg, 30 mg, and 45 mg. These preparations release leuprolide acetate over 1, 3, 4, and 6 months, respectively [<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\">2<\/a>]. Therefore, an Eligard injection containing 7.5 mg of leuprolide acetate needs to be repeated monthly, while an injection that contains 45 mg needs to be given only once every 6 months. All formulations deliver equivalent therapeutic exposure over their respective dosing intervals.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Eligard is administered subcutaneously, in the layer just underneath the skin. Each Eligard pack contains two syringes, and the contents need to be mixed immediately before the injection is administered.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Are_the_Benefits_of_Eligard_Therapy_in_Prostate_Cancer\"><\/span><span style=\"font-weight: 400;\">What Are the Benefits of Eligard Therapy in Prostate Cancer?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">According to the FDA label, Eligard has shown over <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\">95% effectiveness<\/a> in clinical studies in reaching clinically important testosterone suppression (levels below 50 ng\/dl) persistently over the expected duration of benefit. Only 1% \u2013 3% of patients taking Eligard reported a concentration higher than the castrate threshold of 50 ng\/dl [2]. Patients taking Eligard also showed a consistent reduction of 86% \u2013 98% in the prostate-specific antigen (PSA) levels in those studies. PSA is an indicator of prostate cell activity. Reduced PSA levels in prostate cancer indicate lower activity of prostate cancer cells.<\/span><\/p>\n\n\n\n<p>These outcomes support Eligard as an effective and reliable option for long-term androgen deprivation therapy in advanced prostate cancer.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"For_How_Long_Should_You_Take_Eligard_in_Prostate_Cancer\"><\/span><span style=\"font-weight: 400;\">For How Long Should You Take Eligard in Prostate Cancer?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Your doctor may prescribe Eligard for as long as there are benefits. Leuprolide acetate has been used continuously for up to 7 years in some long-term studies [<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/021731s005,021488s010,021379s010,021343s015lbl.pdf\">2<\/a>]. Your doctor may prescribe Eligard in combination with other hormone therapy medications such as <a href=\"https:\/\/ameripharmaspecialty.com\/discontinued\/enzalutamide-xtandi\/\" type=\"link\" id=\"https:\/\/ameripharmaspecialty.com\/discontinued\/enzalutamide-xtandi\/\">Xtandi<\/a> [<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/213674s000lbl.pdf\">7<\/a>], especially early in the therapy, to better manage testosterone levels.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span><span style=\"font-weight: 400;\">Cost<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">The cost of Eligard varies among the four available dosages. Depending on the insurance and pharmacy, the cost of each preparation may further vary. Therefore, the exact cost is difficult to determine until a prescription has been evaluated. In general, however, the cost of a 1-month injection (7.5 mg) of Eligard is around $500.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-663f14f3235da2b48f0ddcba4a0b1746\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Copay_Assistance\"><\/span><span style=\"font-weight: 400;\">Copay Assistance<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Eligible patients with prostate cancer may receive Eligard under the Eligard Patient Assistance Program. Services under this program are provided by Eligard\u2019s manufacturer, Tolmar Inc [<a href=\"https:\/\/eligardhcp.com\/\">8<\/a>]. Speak to an AmeriPharma\u00ae specialist to learn more and <a href=\"https:\/\/ameripharmaspecialty.com\/financial-assistance\/\">apply to copay assistance programs<\/a>.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>El Eligard (acetato de leuprolida) es una terapia hormonal inyectable de acci\u00f3n prolongada que se utiliza en el tratamiento del c\u00e1ncer de pr\u00f3stata avanzado. Act\u00faa suprimiendo la producci\u00f3n de testosterona, un factor clave en el crecimiento del c\u00e1ncer de pr\u00f3stata. Este art\u00edculo analiza las indicaciones, el mecanismo de acci\u00f3n, la dosificaci\u00f3n, los beneficios, los riesgos y las alternativas disponibles del Eligard.<\/p>","protected":false},"author":10,"featured_media":19396,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[13],"tags":[14],"class_list":["post-19395","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-dr-james-lee"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Eligard (Leuprolide Acetate) - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Eligard (leuprolide acetate) is a type of hormone therapy that is used for relieving the symptoms of advanced prostate cancer.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/es\/cancer\/eligard-leuprolide-acetate\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Eligard (Leuprolide Acetate) - 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He attended the University of the Pacific, Thomas J. Long School of Pharmacy and has been a practicing pharmacist for 5 years and is a Board Certified Pharmacotherapy Specialist. The most rewarding part of his job is solving problems. 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